| Cell line name |
SK-MEL-29.1 |
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| Synonyms |
SK29-MEL-1 |
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| Accession |
CVCL_IY54 |
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| Resource Identification Initiative |
To cite this cell line use: SK-MEL-29.1 (RRID:CVCL_IY54) |
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| Comments |
Population: Caucasian.
Derived from site: Metastatic; Axillary lymph node; UBERON=UBERON_0001097. |
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| Sequence variations |
- Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (from parent cell line).
- Mutation; HGNC; HGNC:1773; CDK4; Simple; p.Arg24Cys (c.70C>T); ClinVar=VCV000016928; Zygosity=Heterozygous (PubMed=7652577).
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| HLA typing |
Source: PubMed=9605759
| Class I | | HLA-A | A*02,28 | | HLA-B | B*44,w45 | | HLA-C | C*w5,w6 |
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| Disease |
Melanoma (NCIt: C3224) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_6031 (SK-MEL-29)
Children:
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| Sex of cell |
Male |
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| Age at sampling |
19Y |
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| Category |
Cancer cell line |
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| Publications | PubMed=2784858; DOI=10.1073/pnas.86.8.2804; PMCID=PMC287007
Knuth A., Wolfel T., Klehmann-Hieb E., Boon T., Meyer zum Buschenfelde K.-H.
Cytolytic T-cell clones against an autologous human melanoma: specificity study and definition of three antigens by immunoselection.
Proc. Natl. Acad. Sci. U.S.A. 86:2804-2808(1989) PubMed=7652577; DOI=10.1126/science.7652577
Wolfel T., Hauer M., Schneider J., Serrano M., Wolfel C., Klehmann-Hieb E., De Plaen E., Hankeln T., Meyer zum Buschenfelde K.-H., Beach D.H.
A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma.
Science 269:1281-1284(1995) PubMed=9605759
Wang Z.-G., Seliger B., Mike N., Momburg F., Knuth A., Ferrone S.
Molecular analysis of the HLA-A2 antigen loss by melanoma cells SK-MEL-29.1.22 and SK-MEL-29.1.29.
Cancer Res. 58:2149-2157(1998) |
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| Cross-references |
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| Cell line collections (Providers) |
CLS; 300429
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| Cell line databases/resources |
cancercelllines; CVCL_IY54
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| Encyclopedic resources |
Wikidata; Q54954050
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| Entry history |
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| Entry creation | 15-May-2017 |
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| Last entry update | 19-Dec-2024 |
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| Version number | 10 |
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