ID   SK-MEL-29.1
AC   CVCL_IY54
SY   SK29-MEL-1
DR   cancercelllines; CVCL_IY54
DR   CLS; 300429
DR   Wikidata; Q54954050
RX   PubMed=2784858;
RX   PubMed=7652577;
RX   PubMed=9605759;
CC   Population: Caucasian.
CC   HLA typing: A*02,28; B*44,w45; C*w5,w6 (PubMed=9605759).
CC   Sequence variation: Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:1773; CDK4; Simple; p.Arg24Cys (c.70C>T); ClinVar=VCV000016928; Zygosity=Heterozygous (PubMed=7652577).
CC   Derived from site: Metastatic; Axillary lymph node; UBERON=UBERON_0001097.
DI   NCIt; C3224; Melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_6031 ! SK-MEL-29
SX   Male
AG   19Y
CA   Cancer cell line
DT   Created: 15-05-17; Last updated: 19-12-24; Version: 10
//
RX   PubMed=2784858; DOI=10.1073/pnas.86.8.2804; PMCID=PMC287007;
RA   Knuth A., Wolfel T., Klehmann-Hieb E., Boon T.,
RA   Meyer zum Buschenfelde K.-H.;
RT   "Cytolytic T-cell clones against an autologous human melanoma:
RT   specificity study and definition of three antigens by
RT   immunoselection.";
RL   Proc. Natl. Acad. Sci. U.S.A. 86:2804-2808(1989).
//
RX   PubMed=7652577; DOI=10.1126/science.7652577;
RA   Wolfel T., Hauer M., Schneider J., Serrano M., Wolfel C.,
RA   Klehmann-Hieb E., De Plaen E., Hankeln T.,
RA   Meyer zum Buschenfelde K.-H., Beach D.H.;
RT   "A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T
RT   lymphocytes in a human melanoma.";
RL   Science 269:1281-1284(1995).
//
RX   PubMed=9605759;
RA   Wang Z.-G., Seliger B., Mike N., Momburg F., Knuth A., Ferrone S.;
RT   "Molecular analysis of the HLA-A2 antigen loss by melanoma cells
RT   SK-MEL-29.1.22 and SK-MEL-29.1.29.";
RL   Cancer Res. 58:2149-2157(1998).
//