Cellosaurus cell line UROtsa Cd#3 (CVCL

Cellosaurus UROtsa Cd#3 (CVCL_IX05)

Cross-references
Cell line name	UROtsa Cd#3
Synonyms	UTCd#3; UROtsa_Cd_3
Accession	CVCL_IX05
Resource Identification Initiative	To cite this cell line use: UROtsa Cd#3 (RRID:CVCL_IX05)
Comments	Characteristics: Tumorigenic derivative of UROtsa. Subcutaneous injection of this cell line in nude mice produces tumors. Doubling time: 16.4 +- 1.8 hours (PubMed=19921857). Transformant: ChEBI; CHEBI:48775; Cadmium(2+). Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40). Omics: Transcriptome analysis by microarray. Derived from site: In situ; Urinary bladder, urothelium; UBERON=UBERON_0004645. Cell type: Urothelial cell; CL=CL_0000731.
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0571 (UROtsa)
Sex of cell	Female
Age at sampling	12Y
Category	Transformed cell line
Publications	PubMed=19921857; DOI=10.1021/tx900346q; PMCID=PMC2822111 Somji S., Zhou X.-D., Mehus A., Sens M.A., Garrett S.H., Lutz K.L., Dunlevy J.R., Zheng Y., Sens D.A. Variation of keratin 7 expression and other phenotypic characteristics of independent isolates of cadmium transformed human urothelial cells (UROtsa). Chem. Res. Toxicol. 23:348-356(2010) PubMed=30550540; DOI=10.1371/journal.pone.0207877; PMCID=PMC6294394 Hoggarth Z.E., Osowski D.B., Freeberg B.A., Garrett S.H., Sens D.A., Sens M.A., Zhou X.-D., Zhang K.K., Somji S. The urothelial cell line UROtsa transformed by arsenite and cadmium display basal characteristics associated with muscle invasive urothelial cancers. PLoS ONE 13:E0207877-E0207877(2018)
Encyclopedic resources	Wikidata; Q54991834
Gene expression databases	GEO; GSM659712
Entry history
Entry creation	15-May-2017
Last entry update	29-Jun-2023
Version number	8