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Cellosaurus HBG BC2 (CVCL_IW93)

[Text version]
Cell line name HBG BC2
Synonyms HBG-BC2; HBG, clone BC2; BC2
Accession CVCL_IW93
Resource Identification Initiative To cite this cell line use: HBG BC2 (RRID:CVCL_IW93)
Comments Characteristics: Possesses the capacity of being reversibly differentiated in vitro and of maintaining a relatively higher metabolic rate when in the differentiated state (3 weeks). May be used for repeated toxicity testing on cells in culture.
Karyotypic information: Has lost chromosome Y.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Disease Adult hepatocellular carcinoma (NCIt: C7956)
Adult hepatocellular carcinoma (ORDO: Orphanet_210159)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_IW92 (HBG)
Sex of cell Male
Age at sampling 61Y
Category Cancer cell line
Publications

PubMed=9486853
Glaise D., Ilyin G.P., Loyer P., Cariou S., Bilodeau M., Lucas J., Puisieux A., Ozturk M., Guguen-Guillouzo C.
Cell cycle gene regulation in reversibly differentiated new human hepatoma cell lines.
Cell Growth Differ. 9:165-176(1998)

PubMed=12776925; DOI=10.1023/A:1023304005217
Fabre N., Arrivet E., Trancard J., Bichet N., Roome N.O., Prenez A., Vericat J.-A.
A new hepatoma cell line for toxicity testing at repeated doses.
Cell Biol. Toxicol. 19:71-82(2003)

PubMed=23577442
Fabre N., Arrivet E., Paillard F., Wibaut-Berlaimont V., Bichet N., Roome N.O., Prenez A., Vericat J.-A.
A new human hepatoma cell line to study repeated cell toxicity.
Altern. Lab. Anim. 32 Suppl. 1A:113-116(2004)

Cross-references
Encyclopedic resources Wikidata; Q30133230
Entry history
Entry creation15-May-2017
Last entry update29-Jun-2023
Version number6