ID   HBG BC2
AC   CVCL_IW93
SY   HBG-BC2; HBG, clone BC2; BC2
DR   Wikidata; Q30133230
RX   PubMed=9486853;
RX   PubMed=12776925;
RX   PubMed=23577442;
CC   Characteristics: Possesses the capacity of being reversibly differentiated in vitro and of maintaining a relatively higher metabolic rate when in the differentiated state (3 weeks). May be used for repeated toxicity testing on cells in culture.
CC   Karyotypic information: Has lost chromosome Y.
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
DI   NCIt; C7956; Adult hepatocellular carcinoma
DI   ORDO; Orphanet_210159; Adult hepatocellular carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_IW92 ! HBG
SX   Male
AG   61Y
CA   Cancer cell line
DT   Created: 15-05-17; Last updated: 29-06-23; Version: 6
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RX   PubMed=9486853;
RA   Glaise D., Ilyin G.P., Loyer P., Cariou S., Bilodeau M., Lucas J.,
RA   Puisieux A., Ozturk M., Guguen-Guillouzo C.;
RT   "Cell cycle gene regulation in reversibly differentiated new human
RT   hepatoma cell lines.";
RL   Cell Growth Differ. 9:165-176(1998).
//
RX   PubMed=12776925; DOI=10.1023/A:1023304005217;
RA   Fabre N., Arrivet E., Trancard J., Bichet N., Roome N.O., Prenez A.,
RA   Vericat J.-A.;
RT   "A new hepatoma cell line for toxicity testing at repeated doses.";
RL   Cell Biol. Toxicol. 19:71-82(2003).
//
RX   PubMed=23577442;
RA   Fabre N., Arrivet E., Paillard F., Wibaut-Berlaimont V., Bichet N.,
RA   Roome N.O., Prenez A., Vericat J.-A.;
RT   "A new human hepatoma cell line to study repeated cell toxicity.";
RL   Altern. Lab. Anim. 32 Suppl. 1A:113-116(2004).
//