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Cellosaurus KNBCCS6 E6/E7 (CVCL_IU65)

[Text version]
Cell line name KNBCCS6 E6/E7
Accession CVCL_IU65
Resource Identification Initiative To cite this cell line use: KNBCCS6 E6/E7 (RRID:CVCL_IU65)
Comments Group: Patented cell line.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from site: In situ; Skin, epidermis; UBERON=UBERON_0001003.
Cell type: Keratinocyte; CL=CL_0000312.
Sequence variations
  • Mutation; HGNC; HGNC:9585; PTCH1; Simple; p.Pro643Thrfs*11 (c.1925insC) (H652X); Zygosity=Heterozygous (from parent cell line).
Disease Nevoid basal cell carcinoma syndrome (NCIt: C2892)
Gorlin syndrome (ORDO: Orphanet_377)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_IU64 (KNBCCS6)
Sex of cell Female
Age at sampling 49Y
Category Transformed cell line
Publications

Patent=US20190242874
Burty-Valin E., Magnaldo T., Gache Y., Aubert J.
Human epithelial cell line for 3-D modelizing of cancer and treatment thereof.
Patent number US20190242874, 08-Aug-2019

Cross-references
Encyclopedic resources Wikidata; Q54900247
Entry history
Entry creation03-Mar-2017
Last entry update19-Dec-2024
Version number14