Cellosaurus cell line ID8-Luc2 (CVCL

Cellosaurus ID8-Luc2 (CVCL_IU16)

Cross-references
Cell line name	ID8-Luc2
Synonyms	ID8luc2
Accession	CVCL_IU16
Resource Identification Initiative	To cite this cell line use: ID8-Luc2 (RRID:CVCL_IU16)
Comments	Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Firefly luciferase (Note=With optimized codon usage for mammalian expression). Derived from site: In situ; Ovary, surface epithelium; UBERON=UBERON_0001304. Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 10090) Breed/subspecies: C57BL/6.
Hierarchy	Parent: CVCL_IU14 (ID8)
Sex of cell	Female
Age at sampling	Adult
Category	Spontaneously immortalized cell line
Publications	PubMed=25992288; DOI=10.1186/s40425-015-0060-6; PMCID=PMC4437454 Liao J.B., Ovenell K.J., Curtis E.E.M., Cecil D.L., Koehnlein M.R., Rastetter L.R., Gad E.A., Disis M.L. Preservation of tumor-host immune interactions with luciferase-tagged imaging in a murine model of ovarian cancer. J. Immunother. Cancer 3:16.1-16.9(2015) PubMed=26676113; DOI=10.1186/s40425-015-0102-0; PMCID=PMC4678634 Baert T., Verschuere T., Van Hoylandt A., Gijsbers R., Vergote I., Coosemans A. The dark side of ID8-Luc2: pitfalls for luciferase tagged murine models for ovarian cancer. J. Immunother. Cancer 3:57.1-57.5(2015) PubMed=27235858; DOI=10.1016/j.ygyno.2016.05.028; PMCID=PMC4961516 Hernandez L., Kim M.K., Lyle L.T., Bunch K.P., House C.D., Ning F., Noonan A.M., Annunziata C.M. Characterization of ovarian cancer cell lines as in vivo models for preclinical studies. Gynecol. Oncol. 142:332-340(2016)
Encyclopedic resources	Wikidata; Q54897295
Entry history
Entry creation	03-Mar-2017
Last entry update	10-Sep-2024
Version number	7