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Cellosaurus ID8 (CVCL_IU14)

[Text version]
Cell line name ID8
Synonyms ID8/MOSEC
Accession CVCL_IU14
Resource Identification Initiative To cite this cell line use: ID8 (RRID:CVCL_IU14)
Comments Characteristics: Physiologically and biologically closely resembles human epithelial ovarian cancer.
Derived from site: In situ; Ovary, surface epithelium; UBERON=UBERON_0001304.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
Hierarchy Children:
CVCL_VA22 (ID8-B7H6)CVCL_IU15 (ID8-Fluc)CVCL_C8UV (ID8-Luc)
CVCL_IU16 (ID8-Luc2)CVCL_E0W3 (Ubigene ID8 Arid1a KO)CVCL_E0W4 (Ubigene ID8 Atrx KO)
CVCL_E0W5 (Ubigene ID8 Fat1 KO)CVCL_E0W6 (Ubigene ID8 Hk2 KO)CVCL_E0W7 (Ubigene ID8 Kmt2c KO)
CVCL_E0W8 (Ubigene ID8 Kmt2d KO)CVCL_E0W9 (Ubigene ID8 Rb1 KO)CVCL_E0WA (Ubigene ID8 Smarca4 KO)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
STR profile Source(s): Millipore=SCC145; Ubigene=YC-C103

Markers:
Mouse STR 1-116
Mouse STR 1-220
Mouse STR 2-116
Mouse STR 3-214
Mouse STR 4-219.3
Mouse STR 5-517
Mouse STR 6-418
Mouse STR 6-715
Mouse STR 7-126.2
Mouse STR 8-118
Mouse STR 11-216
Mouse STR 12-117
Mouse STR 13-117
Mouse STR 15-322.3
Mouse STR 17-215
Mouse STR 18-317
Mouse STR 19-213
Mouse STR X-127

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Publications

PubMed=10753190; DOI=10.1093/carcin/21.4.585
Roby K.F., Taylor C.C., Sweetwood J.P., Cheng Y., Pace J.L., Tawfik O., Persons D.L., Smith P.G., Terranova P.F.
Development of a syngeneic mouse model for events related to ovarian cancer.
Carcinogenesis 21:585-591(2000)

PubMed=16886597
Janat-Amsbury M.M., Yockman J.W., Anderson M.L., Kieback D.G., Kim S.W.
Comparison of ID8 MOSE and VEGF-modified ID8 cell lines in an immunocompetent animal model for human ovarian cancer.
Anticancer Res. 26:2785-2789(2006)

PubMed=18036641; DOI=10.1016/j.ygyno.2007.10.035
Greenaway J., Moorehead R., Shaw P., Petrik J.
Epithelial-stromal interaction increases cell proliferation, survival and tumorigenicity in a mouse model of human epithelial ovarian cancer.
Gynecol. Oncol. 108:385-394(2008)

PubMed=27235858; DOI=10.1016/j.ygyno.2016.05.028; PMCID=PMC4961516
Hernandez L., Kim M.K., Lyle L.T., Bunch K.P., House C.D., Ning F., Noonan A.M., Annunziata C.M.
Characterization of ovarian cancer cell lines as in vivo models for preclinical studies.
Gynecol. Oncol. 142:332-340(2016)

Cross-references
Cell line collections (Providers) Millipore; SCC145
Ubigene; YC-C103
Encyclopedic resources Wikidata; Q54897292
Proteomic databases PRIDE; PXD013062
Entry history
Entry creation03-Mar-2017
Last entry update02-May-2024
Version number10