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Cellosaurus IGR-CaP1-R100 (CVCL_IR45)

[Text version]
Cell line name IGR-CaP1-R100
Accession CVCL_IR45
Resource Identification Initiative To cite this cell line use: IGR-CaP1-R100 (RRID:CVCL_IR45)
Comments Group: Patented cell line.
Registration: International Depositary Authority, Pasteur Institute Collection Nationale de Cultures de Micro-organismes (CNCM); I-4127.
Selected for resistance to: ChEBI; CHEBI_4672; Docetaxel anhydrous (Taxotere).
Derived from site: In situ; Prostate; UBERON=UBERON_0002367.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr126Cys (c.377A>G); ClinVar=VCV000458541; Zygosity=Unspecified (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_A018 (IGR-CaP1)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
STR profile Source(s): Patent=US8674172

Markers:
AmelogeninX
CSF1PO11,12,14,15,16
D2S133817,24,25
D3S135814,15
D5S81812,13
D7S8209.1,10.1,11.2
D8S117913,14,16,17
D13S3178,10
D16S53910,11,12,13
D18S5115,16
D19S43313,14
D21S1126,30.2
FGA19,20,21,25
TH016,7,8,9.3
TPOX8,10,11
vWA16,20,21

Run an STR similarity search on this cell line
Publications

Patent=US8674172
Chauchereau A., Fizazi K., Gaudin C., Al Nakouzi N., Benard J.
Prostate cancer cell lines and their use in screening method.
Patent number US8674172, 18-Mar-2014

PubMed=24525428; DOI=10.18632/oncotarget.1574; PMCID=PMC3996665
Al Nakouzi N., Cotteret S., Commo F., Gaudin C., Rajpar S., Dessen P., Vielh P., Fizazi K., Chauchereau A.
Targeting CDC25C, PLK1 and CHEK1 to overcome docetaxel resistance induced by loss of LZTS1 in prostate cancer.
Oncotarget 5:667-678(2014)

Cross-references
Cell line databases/resources cancercelllines; CVCL_IR45
Encyclopedic resources Wikidata; Q54897377
Entry history
Entry creation03-Mar-2017
Last entry update19-Dec-2024
Version number11