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Cellosaurus IGR-CaP1 (CVCL_A018)

[Text version]
Cell line name IGR-CaP1
Synonyms Institut Gustave Roussy-Carcinoma Pancreas 1
Accession CVCL_A018
Resource Identification Initiative To cite this cell line use: IGR-CaP1 (RRID:CVCL_A018)
Comments Group: Patented cell line.
Registration: International Depositary Authority, Pasteur Institute Collection Nationale de Cultures de Micro-organismes (CNCM); I-4126.
Doubling time: 43 hours (PubMed=20974126).
Karyotypic information: Has lost chromosome Y.
Derived from site: In situ; Prostate; UBERON=UBERON_0002367.
Sequence variations
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_WM75 (IGR-CaP1-R-caba)CVCL_IR45 (IGR-CaP1-R100)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
STR profile Source(s): Patent=US8674172; PubMed=20974126

Markers:
AmelogeninX
CSF1PO11,14,16
D2S133817,24,25
D3S135814,15
D5S81812,13
D7S8209.1,10.1,11.2
D8S117913,14,15,16,17
D13S3178,10
D16S53911,12,13
D18S5114,15,16
D19S43313,14
D21S1126,30.2
FGA20,21,25,26
TH017,8,9.3
TPOX8,10,11
vWA16,20,21

Run an STR similarity search on this cell line
Publications

PubMed=20974126; DOI=10.1016/j.yexcr.2010.10.012
Chauchereau A., Al Nakouzi N., Gaudin C., Le Moulec S., Compagno D., Auger N., Benard J., Opolon P., Rozet F., Validire P., Fromont G., Fizazi K.
Stemness markers characterize IGR-CaP1, a new cell line derived from primary epithelial prostate cancer.
Exp. Cell Res. 317:262-275(2011)

Patent=US8674172
Chauchereau A., Fizazi K., Gaudin C., Al Nakouzi N., Benard J.
Prostate cancer cell lines and their use in screening method.
Patent number US8674172, 18-Mar-2014

PubMed=24525428; DOI=10.18632/oncotarget.1574; PMCID=PMC3996665
Al Nakouzi N., Cotteret S., Commo F., Gaudin C., Rajpar S., Dessen P., Vielh P., Fizazi K., Chauchereau A.
Targeting CDC25C, PLK1 and CHEK1 to overcome docetaxel resistance induced by loss of LZTS1 in prostate cancer.
Oncotarget 5:667-678(2014)

PubMed=27198502; DOI=10.15252/emmm.201506059; PMCID=PMC4931290
Al Nakouzi N., Wang C.K.-D., Beraldi E., Jager W., Ettinger S., Fazli L., Nappi L., Bishop J.L., Zhang F., Chauchereau A., Loriot Y., Gleave M.E.
Clusterin knockdown sensitizes prostate cancer cells to taxane by modulating mitosis.
EMBO Mol. Med. 8:761-778(2016)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A018
Encyclopedic resources Wikidata; Q54897375
Polymorphism and mutation databases IARC_TP53; 28239
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number16