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Cellosaurus CL97-L2G (CVCL_IQ77)

[Text version]
Cell line name CL97-L2G
Accession CVCL_IQ77
Resource Identification Initiative To cite this cell line use: CL97-L2G (RRID:CVCL_IQ77)
Comments Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Firefly luciferase.
Genetic integration: Method=Transfection/transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; 3236; EGFR; Simple; p.Gly719Ala (c.2156G>C); ClinVar=VCV000045225; Zygosity=Unspecified (PubMed=23024022).
  • Mutation; HGNC; 3236; EGFR; Simple; p.Thr790Met (c.2369C>T); ClinVar=VCV000016613; Zygosity=Unspecified (PubMed=23024022).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_N826 (CL97)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=23024022; DOI=10.1164/rccm.201207-1180OC
Yeh C.-T., Wu A.T.H., Chang P.M.-H., Chen K.-Y., Yang C.-N., Yang S.-C., Ho C.-C., Chen C.-C., Kuo Y.-L., Lee P.-Y., Liu Y.-W., Yen C.-C., Hsiao M., Lu P.-J., Lai J.-M., Wang L.-S., Wu C.-H., Chiou J.-F., Yang P.-C., Huang C.-Y.F.
Trifluoperazine, an antipsychotic agent, inhibits cancer stem cell growth and overcomes drug resistance of lung cancer.
Am. J. Respir. Crit. Care Med. 186:1180-1188(2012)

Cross-references
Cell line databases/resources cancercelllines; CVCL_IQ77
Encyclopedic resources Wikidata; Q54813530
Entry history
Entry creation03-Mar-2017
Last entry update10-Sep-2024
Version number13