ID   CL97-L2G
AC   CVCL_IQ77
DR   cancercelllines; CVCL_IQ77
DR   Wikidata; Q54813530
RX   PubMed=23024022;
CC   Sequence variation: Mutation; HGNC; 3236; EGFR; Simple; p.Gly719Ala (c.2156G>C); ClinVar=VCV000045225; Zygosity=Unspecified (PubMed=23024022).
CC   Sequence variation: Mutation; HGNC; 3236; EGFR; Simple; p.Thr790Met (c.2369C>T); ClinVar=VCV000016613; Zygosity=Unspecified (PubMed=23024022).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Firefly luciferase.
CC   Genetic integration: Method=Transfection/transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C3512; Lung adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_N826 ! CL97
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 03-03-17; Last updated: 10-09-24; Version: 13
//
RX   PubMed=23024022; DOI=10.1164/rccm.201207-1180OC;
RA   Yeh C.-T., Wu A.T.H., Chang P.M.-H., Chen K.-Y., Yang C.-N.,
RA   Yang S.-C., Ho C.-C., Chen C.-C., Kuo Y.-L., Lee P.-Y., Liu Y.-W.,
RA   Yen C.-C., Hsiao M., Lu P.-J., Lai J.-M., Wang L.-S., Wu C.-H.,
RA   Chiou J.-F., Yang P.-C., Huang C.-Y.F.;
RT   "Trifluoperazine, an antipsychotic agent, inhibits cancer stem cell
RT   growth and overcomes drug resistance of lung cancer.";
RL   Am. J. Respir. Crit. Care Med. 186:1180-1188(2012).
//