Cellosaurus cell line CuFi-2 (CVCL

Cellosaurus CuFi-2 (CVCL_IN82)

Cross-references
Cell line name	CuFi-2
Synonyms	Cystic Fibrosis, University of Iowa-2
Accession	CVCL_IN82
Resource Identification Initiative	To cite this cell line use: CuFi-2 (RRID:CVCL_IN82)
Comments	Karyotypic information: 47,XY,+20 [6]; 48,XY,+5,+20 [2]; 48,XY,i(7)(p10),+20 [2] (PubMed=12676769). Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT. Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6. Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7. Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo. Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16). Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031. Cell type: Epithelial cell of bronchus; CL=CL_0002328.
Sequence variations	Mutation; HGNC; HGNC:1884; CFTR; Simple; p.Phe508del (c.1521_1523delCTT); ClinVar=VCV000007105; Zygosity=Homozygous (PubMed=12676769).
Disease	Cystic fibrosis (NCIt: C2975) Cystic fibrosis (ORDO: Orphanet_586)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	Age unspecified
Category	Transformed cell line
Publications	PubMed=12676769; DOI=10.1152/ajplung.00355.2002 Zabner J., Karp P., Seiler M., Phillips S.L., Mitchell C.J., Saavedra M.T., Welsh M., Klingelhutz A.J. Development of cystic fibrosis and noncystic fibrosis airway cell lines. Am. J. Physiol. Lung Cell. Mol. Physiol. 284:L844-L854(2003)
Encyclopedic resources	Wikidata; Q54814855
Entry history
Entry creation	01-Dec-2016
Last entry update	19-Dec-2024
Version number	16