ID   CuFi-2
AC   CVCL_IN82
SY   Cystic Fibrosis, University of Iowa-2
DR   Wikidata; Q54814855
RX   PubMed=12676769;
CC   Karyotypic information: 47,XY,+20 [6]; 48,XY,+5,+20 [2]; 48,XY,i(7)(p10),+20 [2] (PubMed=12676769).
CC   Sequence variation: Mutation; HGNC; HGNC:1884; CFTR; Simple; p.Phe508del (c.1521_1523delCTT); ClinVar=VCV000007105; Zygosity=Homozygous (PubMed=12676769).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
CC   Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031.
CC   Cell type: Epithelial cell of bronchus; CL=CL_0002328.
DI   NCIt; C2975; Cystic fibrosis
DI   ORDO; Orphanet_586; Cystic fibrosis
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   Age unspecified
CA   Transformed cell line
DT   Created: 01-12-16; Last updated: 19-12-24; Version: 16
//
RX   PubMed=12676769; DOI=10.1152/ajplung.00355.2002;
RA   Zabner J., Karp P., Seiler M., Phillips S.L., Mitchell C.J.,
RA   Saavedra M.T., Welsh M., Klingelhutz A.J.;
RT   "Development of cystic fibrosis and noncystic fibrosis airway cell
RT   lines.";
RL   Am. J. Physiol. Lung Cell. Mol. Physiol. 284:L844-L854(2003).
//