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Cellosaurus mTEC1-CF (CVCL_IN78)

[Text version]
Cell line name mTEC1-CF
Accession CVCL_IN78
Resource Identification Initiative To cite this cell line use: mTEC1-CF (RRID:CVCL_IN78)
Comments Knockout cell: Method=KO mouse; MGI; MGI:88388; Cftr.
Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; SV40 large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
Derived from site: In situ; Trachea, epithelium; UBERON=UBERON_0001901.
Cell type: Epithelial cell of trachea; CL=CL_0000307.
Sequence variations
  • Mutation; MGI; MGI:88388; Cftr; Simple; p.Ser489Ter (c.1466C>A); Zygosity=Homozygous (PubMed=11121394).
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: [(CBA/Ca x C57BL/10)Tg(H2Kb-tsA58) Immortomouse x (C57BL/6J x 129)Cftr-/-].
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Conditionally immortalized cell line
Publications

PubMed=11121394; DOI=10.1152/ajpcell.2001.280.1.C228
Takacs-Jarrett M., Sweeney W.E., Avner E.D., Cotton C.U.
Generation and phenotype of cell lines derived from CF and non-CF mice that carry the H-2K(b)-tsA58 transgene.
Am. J. Physiol. Cell Physiol. 280:C228-C236(2001)

PubMed=15463957; DOI=10.1016/j.jcf.2004.05.040
Gruenert D.C., Willems M., Cassiman J.-J., Frizzell R.A.
Established cell lines used in cystic fibrosis research.
J. Cyst. Fibros. 3:191-196(2004)

Cross-references
Encyclopedic resources Wikidata; Q54906998
Entry history
Entry creation01-Dec-2016
Last entry update10-Sep-2024
Version number11