ID   mTEC1-CF
AC   CVCL_IN78
DR   Wikidata; Q54906998
RX   PubMed=11121394;
RX   PubMed=15463957;
CC   Knockout cell: Method=KO mouse; MGI; MGI:88388; Cftr.
CC   Sequence variation: Mutation; MGI; MGI:88388; Cftr; Simple; p.Ser489Ter (c.1466C>A); Zygosity=Homozygous (PubMed=11121394).
CC   Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
CC   Derived from site: In situ; Trachea, epithelium; UBERON=UBERON_0001901.
CC   Cell type: Epithelial cell of trachea; CL=CL_0000307.
CC   Breed/subspecies: [(CBA/Ca x C57BL/10)Tg(H2Kb-tsA58) Immortomouse x (C57BL/6J x 129)Cftr-/-].
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Sex unspecified
AG   Age unspecified
CA   Conditionally immortalized cell line
DT   Created: 01-12-16; Last updated: 10-09-24; Version: 11
//
RX   PubMed=11121394; DOI=10.1152/ajpcell.2001.280.1.C228;
RA   Takacs-Jarrett M., Sweeney W.E., Avner E.D., Cotton C.U.;
RT   "Generation and phenotype of cell lines derived from CF and non-CF
RT   mice that carry the H-2K(b)-tsA58 transgene.";
RL   Am. J. Physiol. Cell Physiol. 280:C228-C236(2001).
//
RX   PubMed=15463957; DOI=10.1016/j.jcf.2004.05.040;
RA   Gruenert D.C., Willems M., Cassiman J.-J., Frizzell R.A.;
RT   "Established cell lines used in cystic fibrosis research.";
RL   J. Cyst. Fibros. 3:191-196(2004).
//