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Cellosaurus CFTE29o- (CVCL_IN57)

[Text version]
Cell line name CFTE29o-
Synonyms CFTE29o(-); CFTE-29o-; EpsilonCFTE29o-; ECFTE29o-
Accession CVCL_IN57
Resource Identification Initiative To cite this cell line use: CFTE29o- (RRID:CVCL_IN57)
Comments Characteristics: Useful model for cystic fibrosis and for studying chloride ion transport and ion transport in human airways. The cells are useful for testing candidate chemotherapeutic drugs for their potential as treatments for ameliorating CF pathologies (Millipore=SCC162).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSVori-).
Sequence variations
Disease Cystic fibrosis (NCIt: C2975)
Cystic fibrosis (ORDO: Orphanet_586)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 21Y
Category Transformed cell line
STR profile Source(s): Millipore=SCC162

Markers:
AmelogeninX
CSF1PO10,13
D3S135815,16
D5S81811,12
D7S82010,11
D8S117915
D13S3179,11
D16S53910,12
D18S5114
D21S1128,31.2
FGA24,26
Penta D10,12
Penta E7,12
TH017,9
TPOX8,11
vWA17

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Web pages https://web.archive.org/web/20190126194809/http://www.dartmouth.edu/~cysfib/cell-lines.html
Publications

PubMed=7683197; DOI=10.1165/ajrcmb/8.5.522
Kunzelmann K., Schwiebert E.M., Zeitlin P.L., Kuo W.-L., Stanton B.A., Gruenert D.C.
An immortalized cystic fibrosis tracheal epithelial cell line homozygous for the delta F508 CFTR mutation.
Am. J. Respir. Cell Mol. Biol. 8:522-529(1993)

PubMed=15463957; DOI=10.1016/j.jcf.2004.05.040
Gruenert D.C., Willems M., Cassiman J.-J., Frizzell R.A.
Established cell lines used in cystic fibrosis research.
J. Cyst. Fibros. 3:191-196(2004)

Cross-references
Cell line collections (Providers) Millipore; SCC162
Encyclopedic resources Wikidata; Q54811463
Entry history
Entry creation01-Dec-2016
Last entry update19-Dec-2024
Version number14