ID   CFTE29o-
AC   CVCL_IN57
SY   CFTE29o(-); CFTE-29o-; EpsilonCFTE29o-; ECFTE29o-
DR   Millipore; SCC162
DR   Wikidata; Q54811463
RX   PubMed=7683197;
RX   PubMed=15463957;
WW   https://web.archive.org/web/20190126194809/http://www.dartmouth.edu/~cysfib/cell-lines.html
CC   Characteristics: Useful model for cystic fibrosis and for studying chloride ion transport and ion transport in human airways. The cells are useful for testing candidate chemotherapeutic drugs for their potential as treatments for ameliorating CF pathologies (Millipore=SCC162).
CC   Sequence variation: Mutation; HGNC; HGNC:1884; CFTR; Simple; p.Phe508del (c.1521_1523delCTT); ClinVar=VCV000007105; Zygosity=Homozygous (PubMed=7683197; PubMed=15463957).
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSVori-).
ST   Source(s): Millipore=SCC162
ST   Amelogenin: X
ST   CSF1PO: 10,13
ST   D13S317: 9,11
ST   D16S539: 10,12
ST   D18S51: 14
ST   D21S11: 28,31.2
ST   D3S1358: 15,16
ST   D5S818: 11,12
ST   D7S820: 10,11
ST   D8S1179: 15
ST   FGA: 24,26
ST   Penta D: 10,12
ST   Penta E: 7,12
ST   TH01: 7,9
ST   TPOX: 8,11
ST   vWA: 17
DI   NCIt; C2975; Cystic fibrosis
DI   ORDO; Orphanet_586; Cystic fibrosis
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   21Y
CA   Transformed cell line
DT   Created: 01-12-16; Last updated: 19-12-24; Version: 14
//
RX   PubMed=7683197; DOI=10.1165/ajrcmb/8.5.522;
RA   Kunzelmann K., Schwiebert E.M., Zeitlin P.L., Kuo W.-L., Stanton B.A.,
RA   Gruenert D.C.;
RT   "An immortalized cystic fibrosis tracheal epithelial cell line
RT   homozygous for the delta F508 CFTR mutation.";
RL   Am. J. Respir. Cell Mol. Biol. 8:522-529(1993).
//
RX   PubMed=15463957; DOI=10.1016/j.jcf.2004.05.040;
RA   Gruenert D.C., Willems M., Cassiman J.-J., Frizzell R.A.;
RT   "Established cell lines used in cystic fibrosis research.";
RL   J. Cyst. Fibros. 3:191-196(2004).
//