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Cellosaurus PT-r (CVCL_HF63)

[Text version]
Cell line name PT-r
Accession CVCL_HF63
Resource Identification Initiative To cite this cell line use: PT-r (RRID:CVCL_HF63)
Comments Doubling time: ~20 hours (PubMed=3472208).
Derived from site: In situ; Parathyroid gland; UBERON=UBERON_0001132.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Sprague Dawley; RS=RS:0000681.
Hierarchy Children:
CVCL_HF64 (PT-r 1)CVCL_HF65 (PT-r 2)CVCL_HF66 (PT-r 3)
CVCL_HF67 (PT-r 4)CVCL_HF62 (PTH-C1)
Sex of cell Male
Age at sampling 3M
Category Spontaneously immortalized cell line
Publications

PubMed=3472208; DOI=10.1073/pnas.84.10.3269; PMCID=PMC304850
Sakaguchi K., Santora A., Zimering M., Curcio F., Aurbach G.D., Brandi M.L.
Functional epithelial cell line cloned from rat parathyroid glands.
Proc. Natl. Acad. Sci. U.S.A. 84:3269-3273(1987)

PubMed=2768284; DOI=10.1016/S0021-9258(19)84891-3
Yanagishita M., Brandi M.L., Sakaguchi K.
Characterization of proteoglycans synthesized by a rat parathyroid cell line.
J. Biol. Chem. 264:15714-15720(1989)

PubMed=1700579; DOI=10.1002/jbmr.5650050810
Sakaguchi K., Ikeda K., Curcio F., Aurbach G.D., Brandi M.L.
Subclones of a rat parathyroid cell line (PT-r): regulation of growth and production of parathyroid hormone-related peptide (PTHRP).
J. Bone Miner. Res. 5:863-869(1990)

PubMed=20558332; DOI=10.1016/j.bone.2010.05.031
Kawahara M., Iwasaki Y., Sakaguchi K., Taguchi T., Nishiyama M., Nigawara T., Kambayashi M., Sawada T., Jing X.-F., Miyajima M., Terada Y., Hashimoto K., Suda T.
Involvement of GCMB in the transcriptional regulation of the human parathyroid hormone gene in a parathyroid-derived cell line PT-r: effects of calcium and 1,25(OH)2D3.
Bone 47:534-541(2010)

PubMed=24627164; DOI=10.1007/s12020-014-0229-7
Fabbri S., Ciuffi S., Nardone V., Gomes A.R., Mavilia C., Zonefrati R., Galli G., Luzi E., Tanini A., Brandi M.L.
PTH-C1: a rat continuous cell line expressing the parathyroid phenotype.
Endocrine 47:90-99(2014)

Cross-references
Cell line collections (Providers) RCB; RCB4548
Encyclopedic resources Wikidata; Q54948626
Entry history
Entry creation01-Dec-2016
Last entry update10-Sep-2024
Version number7