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Cellosaurus ImKC (CVCL_HF55)

[Text version]
Cell line name ImKC
Synonyms Immortalized Kupffer Cells
Accession CVCL_HF55
Resource Identification Initiative To cite this cell line use: ImKC (RRID:CVCL_HF55)
Comments Problematic cell line: Contaminated. Shown to be a RAW 264.7 derivative (Millipore; ICLAC). This is based on the STR profile. Originally thought to be a SV40 immortalized liver kupffer cell from a (CBA/Ca x C57BL/10)Tg(H2Kb-tsA58) Immortomouse.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00620.
Doubling time: ~24 hours (PubMed=25138015); 19-29 hours (ABM=T0062).
Transformant: NCBI_TaxID; 11788; Abelson mouse leukemia virus (AbMuLV).
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Cell type: Macrophage; CL=CL_0000235.
Disease Mouse leukemia (NCIt: C21604)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: BALB/c.
Hierarchy Parent: CVCL_0493 (RAW 264.7)
Sex of cell Male
Age at sampling Adult
Category Cancer cell line
STR profile Source(s): Millipore

Mouse STR 1-115,16
Mouse STR 1-217
Mouse STR 2-116
Mouse STR 3-214
Mouse STR 4-222.3
Mouse STR 5-514
Mouse STR 6-418
Mouse STR 6-712
Mouse STR 7-125.2
Mouse STR 8-113
Mouse STR 11-217
Mouse STR 12-116
Mouse STR 13-116.2
Mouse STR 15-322.3
Mouse STR 17-214,16
Mouse STR 18-318
Mouse STR 19-214
Mouse STR X-124

Run an STR similarity search on this cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx

PubMed=25138015; DOI=10.1016/j.cyto.2014.07.251
Wang Z.-Y., Burlak C., Klaunig J.E., Kamendulis L.M.
Development of a cytokine-producing immortalized murine Kupffer cell line.
Cytokine 70:165-172(2014)

Cell line collections (Providers) ABM; T0062 - Discontinued
Millipore; SCC119 - Discontinued
Encyclopedic resources Wikidata; Q54897590
Entry history
Entry creation01-Dec-2016
Last entry update29-Jun-2023
Version number9