SY   Immortalized Kupffer Cells
DR   ABM; T0062
DR   Millipore; SCC119
DR   Wikidata; Q54897590
RX   PubMed=25138015;
CC   Problematic cell line: Contaminated. Shown to be a RAW 264.7 derivative (Millipore; ICLAC). This is based on the STR profile. Originally thought to be a SV40 immortalized liver kupffer cell from a (CBA/Ca x C57BL/10)Tg(H2Kb-tsA58) Immortomouse.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00620.
CC   Doubling time: ~24 hours (PubMed=25138015); 19-29 hours (ABM=T0062).
CC   Transformant: NCBI_TaxID; 11788; Abelson mouse leukemia virus (AbMuLV).
CC   Discontinued: ABM; T0062; probable.
CC   Discontinued: Millipore; SCC119; true.
CC   Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
CC   Cell type: Macrophage; CL=CL_0000235.
CC   Breed/subspecies: BALB/c.
ST   Source(s): Millipore
ST   Mouse STR 1-1: 15,16
ST   Mouse STR 1-2: 17
ST   Mouse STR 11-2: 17
ST   Mouse STR 12-1: 16
ST   Mouse STR 13-1: 16.2
ST   Mouse STR 15-3: 22.3
ST   Mouse STR 17-2: 14,16
ST   Mouse STR 18-3: 18
ST   Mouse STR 19-2: 14
ST   Mouse STR 2-1: 16
ST   Mouse STR 3-2: 14
ST   Mouse STR 4-2: 22.3
ST   Mouse STR 5-5: 14
ST   Mouse STR 6-4: 18
ST   Mouse STR 6-7: 12
ST   Mouse STR 7-1: 25.2
ST   Mouse STR 8-1: 13
ST   Mouse STR X-1: 24
DI   NCIt; C21604; Mouse leukemia
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_0493 ! RAW 264.7
SX   Male
AG   Adult
CA   Cancer cell line
DT   Created: 01-12-16; Last updated: 29-06-23; Version: 9
RX   PubMed=25138015; DOI=10.1016/j.cyto.2014.07.251;
RA   Wang Z.-Y., Burlak C., Klaunig J.E., Kamendulis L.M.;
RT   "Development of a cytokine-producing immortalized murine Kupffer cell
RT   line.";
RL   Cytokine 70:165-172(2014).