Cellosaurus DLD-1 KRAS(+/-) 1 (CVCL_HD62)
| Cell line name | DLD-1 KRAS(+/-) 1 |
|---|---|
| Synonyms | KRAS (+/-) DLD-1 |
| Accession | CVCL_HD62 |
| Resource Identification Initiative | To cite this cell line use: DLD-1 KRAS(+/-) 1 (RRID:CVCL_HD62) |
| Comments | Population: Caucasian. Characteristics: In DLD-1 one of the two KRAS alleles has a p.Gly13Asp mutation. This cell line is KO for the mutant allele. Knockout cell: Method=Homologous recombination; HGNC; 6407; KRAS (Note=1 of 2 alleles, that with p.Gly13Asp). Miscellaneous: Horizon distributes two DLD-1 KRAS(+/-) cell lines, one developed internally (Cellosaurus=CVCL_HE28) and one originating from the group of Volgenstein (Cellosaurus=CVCL_HD62). Derived from site: In situ; Colon; UBERON=UBERON_0001155. Cell type: Epithelial cell of colon; CL=CL_0011108. |
| Disease | Colon adenocarcinoma (NCIt: C4349) |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_0248 (DLD-1) |
| Sex of cell | Male |
| Age at sampling | 67Y |
| Category | Cancer cell line |
| Publications | PubMed=19661383; DOI=10.1126/science.1174229; PMCID=PMC2820374 |
| Cross-references | |
| Cell line collections (Providers) | Horizon_Discovery; HD+105-002 |
| Encyclopedic resources | Wikidata; Q54831162 |
| Entry history | |
| Entry creation | 01-Dec-2016 |
| Last entry update | 02-May-2024 |
| Version number | 8 |