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Cellosaurus Meso56 (CVCL_H681)

[Text version]
Cell line name Meso56
Synonyms MESO56; Meso 56
Accession CVCL_H681
Resource Identification Initiative To cite this cell line use: Meso56 (RRID:CVCL_H681)
Comments Virology: Susceptible to infection by measles virus that leads to cell death (PubMed=26539644).
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (PubMed=21642991).
Disease Pleural epithelioid mesothelioma (NCIt: C45662)
Pleural mesothelioma (ORDO: Orphanet_50251)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 79Y
Category Cancer cell line
Publications

PubMed=21356356; DOI=10.1016/j.ajpath.2010.12.014; PMCID=PMC3070574
Gueugnon F., Leclercq S., Blanquart C., Sagan C., Cellerin L., Padieu M., Perigaud C., Scherpereel A., Gregoire M.
Identification of novel markers for the diagnosis of malignant pleural mesothelioma.
Am. J. Pathol. 178:1033-1042(2011)

PubMed=21540305; DOI=10.1183/09031936.00160210
Roulois D., Vignard V., Gueugnon F., Labarriere N., Gregoire M., Fonteneau J.-F.
Recognition of pleural mesothelioma by mucin-1(950-958)/human leukocyte antigen A*0201-specific CD8+ T-cells.
Eur. Respir. J. 38:1117-1126(2011)

PubMed=21642991; DOI=10.1038/ng.855; PMCID=PMC4643098
Bott M.J., Brevet M., Taylor B.S., Shimizu S., Ito T., Wang L., Creaney J., Lake R.A., Zakowski M.F., Reva B., Sander C., Delsite R., Powell S.N., Zhou Q., Shen R.-L., Olshen A.B., Rusch V.W., Ladanyi M.
The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma.
Nat. Genet. 43:668-672(2011)

PubMed=21774103; DOI=10.1097/JTO.0b013e318215a07d
Brevet M., Shimizu S., Bott M.J., Shukla N., Zhou Q., Olshen A.B., Rusch V.W., Ladanyi M.
Coactivation of receptor tyrosine kinases in malignant mesothelioma as a rationale for combination targeted therapy.
J. Thorac. Oncol. 6:864-874(2011)

PubMed=26539644; DOI=10.18632/oncotarget.6285; PMCID=PMC4792599
Achard C., Boisgerault N., Delaunay T., Roulois D., Nedellec S., Royer P.-J., Pain M., Combredet C., Mesel-Lemoine M., Cellerin L., Magnan A., Tangy F., Gregoire M., Fonteneau J.-F.
Sensitivity of human pleural mesothelioma to oncolytic measles virus depends on defects of the type I interferon response.
Oncotarget 6:44892-44904(2015)

Cross-references
Cell line databases/resources cancercelllines; CVCL_H681
Biological sample resources BioSamples; SAMEA100840
Encyclopedic resources Wikidata; Q54905312
Gene expression databases GEO; GSM433123
GEO; GSM433141
GEO; GSM433159
GEO; GSM726277
GEO; GSM5342333
Polymorphism and mutation databases Cosmic; 1522782
Cosmic; 1541206
Progenetix; CVCL_H681
Entry history
Entry creation11-Feb-2013
Last entry update10-Sep-2024
Version number14