ID   Meso56
AC   CVCL_H681
SY   MESO56; Meso 56
DR   BioSamples; SAMEA100840
DR   cancercelllines; CVCL_H681
DR   Cosmic; 1522782
DR   Cosmic; 1541206
DR   GEO; GSM433123
DR   GEO; GSM433141
DR   GEO; GSM433159
DR   GEO; GSM726277
DR   GEO; GSM5342333
DR   Progenetix; CVCL_H681
DR   Wikidata; Q54905312
RX   PubMed=21356356;
RX   PubMed=21540305;
RX   PubMed=21642991;
RX   PubMed=21774103;
RX   PubMed=26539644;
CC   Virology: Susceptible to infection by measles virus that leads to cell death (PubMed=26539644).
CC   Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (PubMed=21642991).
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C45662; Pleural epithelioid mesothelioma
DI   ORDO; Orphanet_50251; Pleural mesothelioma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   79Y
CA   Cancer cell line
DT   Created: 11-02-13; Last updated: 10-09-24; Version: 14
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RX   PubMed=21356356; DOI=10.1016/j.ajpath.2010.12.014; PMCID=PMC3070574;
RA   Gueugnon F., Leclercq S., Blanquart C., Sagan C., Cellerin L.,
RA   Padieu M., Perigaud C., Scherpereel A., Gregoire M.;
RT   "Identification of novel markers for the diagnosis of malignant
RT   pleural mesothelioma.";
RL   Am. J. Pathol. 178:1033-1042(2011).
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RX   PubMed=21540305; DOI=10.1183/09031936.00160210;
RA   Roulois D., Vignard V., Gueugnon F., Labarriere N., Gregoire M.,
RA   Fonteneau J.-F.;
RT   "Recognition of pleural mesothelioma by mucin-1(950-958)/human
RT   leukocyte antigen A*0201-specific CD8+ T-cells.";
RL   Eur. Respir. J. 38:1117-1126(2011).
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RX   PubMed=21642991; DOI=10.1038/ng.855; PMCID=PMC4643098;
RA   Bott M.J., Brevet M., Taylor B.S., Shimizu S., Ito T., Wang L.,
RA   Creaney J., Lake R.A., Zakowski M.F., Reva B., Sander C., Delsite R.,
RA   Powell S.N., Zhou Q., Shen R.-L., Olshen A.B., Rusch V.W., Ladanyi M.;
RT   "The nuclear deubiquitinase BAP1 is commonly inactivated by somatic
RT   mutations and 3p21.1 losses in malignant pleural mesothelioma.";
RL   Nat. Genet. 43:668-672(2011).
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RX   PubMed=21774103; DOI=10.1097/JTO.0b013e318215a07d;
RA   Brevet M., Shimizu S., Bott M.J., Shukla N., Zhou Q., Olshen A.B.,
RA   Rusch V.W., Ladanyi M.;
RT   "Coactivation of receptor tyrosine kinases in malignant mesothelioma
RT   as a rationale for combination targeted therapy.";
RL   J. Thorac. Oncol. 6:864-874(2011).
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RX   PubMed=26539644; DOI=10.18632/oncotarget.6285; PMCID=PMC4792599;
RA   Achard C., Boisgerault N., Delaunay T., Roulois D., Nedellec S.,
RA   Royer P.-J., Pain M., Combredet C., Mesel-Lemoine M., Cellerin L.,
RA   Magnan A., Tangy F., Gregoire M., Fonteneau J.-F.;
RT   "Sensitivity of human pleural mesothelioma to oncolytic measles virus
RT   depends on defects of the type I interferon response.";
RL   Oncotarget 6:44892-44904(2015).
//