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Cellosaurus Meso37 (CVCL_H677)

[Text version]
Cell line name Meso37
Synonyms MESO37; Meso 37
Accession CVCL_H677
Resource Identification Initiative To cite this cell line use: Meso37 (RRID:CVCL_H677)
Comments Virology: Susceptible to infection by measles virus that leads to cell death (PubMed=26539644).
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Sequence variations
  • Mutation; HGNC; 950; BAP1; Simple; p.Glu54Ter (c.160G>T); Zygosity=Heterozygous (PubMed=21642991).
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Heterozygous (PubMed=21642991).
Disease Pleural malignant mesothelioma (NCIt: C7376)
Pleural mesothelioma (ORDO: Orphanet_50251)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 65Y
Category Cancer cell line
Publications

PubMed=21356356; DOI=10.1016/j.ajpath.2010.12.014; PMCID=PMC3070574
Gueugnon F., Leclercq S., Blanquart C., Sagan C., Cellerin L., Padieu M., Perigaud C., Scherpereel A., Gregoire M.
Identification of novel markers for the diagnosis of malignant pleural mesothelioma.
Am. J. Pathol. 178:1033-1042(2011)

PubMed=21642991; DOI=10.1038/ng.855; PMCID=PMC4643098
Bott M.J., Brevet M., Taylor B.S., Shimizu S., Ito T., Wang L., Creaney J., Lake R.A., Zakowski M.F., Reva B., Sander C., Delsite R., Powell S.N., Zhou Q., Shen R.-L., Olshen A.B., Rusch V.W., Ladanyi M.
The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma.
Nat. Genet. 43:668-672(2011)

PubMed=21774103; DOI=10.1097/JTO.0b013e318215a07d
Brevet M., Shimizu S., Bott M.J., Shukla N., Zhou Q., Olshen A.B., Rusch V.W., Ladanyi M.
Coactivation of receptor tyrosine kinases in malignant mesothelioma as a rationale for combination targeted therapy.
J. Thorac. Oncol. 6:864-874(2011)

PubMed=26539644; DOI=10.18632/oncotarget.6285; PMCID=PMC4792599
Achard C., Boisgerault N., Delaunay T., Roulois D., Nedellec S., Royer P.-J., Pain M., Combredet C., Mesel-Lemoine M., Cellerin L., Magnan A., Tangy F., Gregoire M., Fonteneau J.-F.
Sensitivity of human pleural mesothelioma to oncolytic measles virus depends on defects of the type I interferon response.
Oncotarget 6:44892-44904(2015)

Cross-references
Cell line databases/resources cancercelllines; CVCL_H677
Biological sample resources BioSamples; SAMEA100816
Encyclopedic resources Wikidata; Q54905308
Gene expression databases GEO; GSM433120
GEO; GSM433138
GEO; GSM433156
GEO; GSM726276
GEO; GSM5342329
Polymorphism and mutation databases Cosmic; 1522761
Cosmic; 1541204
Progenetix; CVCL_H677
Entry history
Entry creation11-Feb-2013
Last entry update10-Sep-2024
Version number16