ID   Meso37
AC   CVCL_H677
SY   MESO37; Meso 37
DR   BioSamples; SAMEA100816
DR   cancercelllines; CVCL_H677
DR   Cosmic; 1522761
DR   Cosmic; 1541204
DR   GEO; GSM433120
DR   GEO; GSM433138
DR   GEO; GSM433156
DR   GEO; GSM726276
DR   GEO; GSM5342329
DR   Progenetix; CVCL_H677
DR   Wikidata; Q54905308
RX   PubMed=21356356;
RX   PubMed=21642991;
RX   PubMed=21774103;
RX   PubMed=26539644;
CC   Virology: Susceptible to infection by measles virus that leads to cell death (PubMed=26539644).
CC   Sequence variation: Mutation; HGNC; 950; BAP1; Simple; p.Glu54Ter (c.160G>T); Zygosity=Heterozygous (PubMed=21642991).
CC   Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Heterozygous (PubMed=21642991).
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis by microarray.
DI   NCIt; C7376; Pleural malignant mesothelioma
DI   ORDO; Orphanet_50251; Pleural mesothelioma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   65Y
CA   Cancer cell line
DT   Created: 11-02-13; Last updated: 10-09-24; Version: 16
//
RX   PubMed=21356356; DOI=10.1016/j.ajpath.2010.12.014; PMCID=PMC3070574;
RA   Gueugnon F., Leclercq S., Blanquart C., Sagan C., Cellerin L.,
RA   Padieu M., Perigaud C., Scherpereel A., Gregoire M.;
RT   "Identification of novel markers for the diagnosis of malignant
RT   pleural mesothelioma.";
RL   Am. J. Pathol. 178:1033-1042(2011).
//
RX   PubMed=21642991; DOI=10.1038/ng.855; PMCID=PMC4643098;
RA   Bott M.J., Brevet M., Taylor B.S., Shimizu S., Ito T., Wang L.,
RA   Creaney J., Lake R.A., Zakowski M.F., Reva B., Sander C., Delsite R.,
RA   Powell S.N., Zhou Q., Shen R.-L., Olshen A.B., Rusch V.W., Ladanyi M.;
RT   "The nuclear deubiquitinase BAP1 is commonly inactivated by somatic
RT   mutations and 3p21.1 losses in malignant pleural mesothelioma.";
RL   Nat. Genet. 43:668-672(2011).
//
RX   PubMed=21774103; DOI=10.1097/JTO.0b013e318215a07d;
RA   Brevet M., Shimizu S., Bott M.J., Shukla N., Zhou Q., Olshen A.B.,
RA   Rusch V.W., Ladanyi M.;
RT   "Coactivation of receptor tyrosine kinases in malignant mesothelioma
RT   as a rationale for combination targeted therapy.";
RL   J. Thorac. Oncol. 6:864-874(2011).
//
RX   PubMed=26539644; DOI=10.18632/oncotarget.6285; PMCID=PMC4792599;
RA   Achard C., Boisgerault N., Delaunay T., Roulois D., Nedellec S.,
RA   Royer P.-J., Pain M., Combredet C., Mesel-Lemoine M., Cellerin L.,
RA   Magnan A., Tangy F., Gregoire M., Fonteneau J.-F.;
RT   "Sensitivity of human pleural mesothelioma to oncolytic measles virus
RT   depends on defects of the type I interferon response.";
RL   Oncotarget 6:44892-44904(2015).
//