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Cellosaurus GM1500-6TG-A11 (CVCL_H615)

[Text version]
Cell line name GM1500-6TG-A11
Synonyms GM1500 6TG-A11; GM 1500 6TG-A11; GM 1500 6TG A11; GM1500 6TG A-11; GM 1500 6TG-A1 1; 6TG-A11; GM04672; GM 4672; GM4672; GM04672B
Accession CVCL_H615
Secondary accession CVCL_F607
Resource Identification Initiative To cite this cell line use: GM1500-6TG-A11 (RRID:CVCL_H615)
Comments Group: Hybridoma fusion partner cell line.
Group: Patented cell line.
Problematic cell line: Misclassified. Parent cell line (GM01500) was originally thought to be a myeloma cell line but is a B-lymphoblastoid cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-8032.
Population: Caucasian.
Characteristics: Secretes IgG2 kappa (Coriell=GM04672).
Selected for resistance to: ChEBI; CHEBI:9555; Tioguanine (6-thioguanine; 6-TG).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Transformant: ChEBI; CHEBI:23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Misspelling: GM1500-GTG-A11; Note=Occasionally.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_D870 (GM01500)
CVCL_H617 (GM1500-6TG-OUB)CVCL_2526 (HuNS1)
Sex of cell Male
Age at sampling Age unspecified
Category Transformed cell line

PubMed=6969366; DOI=10.1038/288488a0
Croce C.M., Linnenbach A., Hall W., Steplewski Z., Koprowski H.
Production of human hybridomas secreting antibodies to measles virus.
Nature 288:488-489(1980)

PubMed=7085884; DOI=10.1172/JCI110595
Shoenfeld Y., Hsu-Lin S.C., Gabriels J.E., Silberstein L.E., Furie B.C., Furie B.E., Stollar B.D., Schwartz R.S.
Production of autoantibodies by human-human hybridomas.
J. Clin. Invest. 70:205-208(1982)

PubMed=6350451; DOI=10.4049/jimmunol.131.3.1201
Abrams P.G., Knost J.A., Clarke G., Wilburn S., Oldham R.K., Foon K.A.
Determination of the optimal human cell lines for development of human hybridomas.
J. Immunol. 131:1201-1204(1983)

PubMed=6864164; DOI=10.1084/jem.158.1.53
Houghton A.N., Brooks H., Cote R.J., Taormina M.C., Oettgen H.F., Old L.J.
Detection of cell surface and intracellular antigens by human monoclonal antibodies. Hybrid cell lines derived from lymphocytes of patients with malignant melanoma.
J. Exp. Med. 158:53-65(1983)

Croce C.M.
Human hybridomas and the production of human monoclonal antibodies by human hybridomas.
Patent number US4608337, 26-Aug-1986

Mulivor R.A., Suchy S.F.
1992/1993 catalog of cell lines. NIGMS human genetic mutant cell repository. 16th edition. October 1992.
(In) Institute for Medical Research (Camden, N.J.) NIH 92-2011; pp.1-918; National Institutes of Health; Bethesda (1992)

PubMed=7689347; DOI=10.3233/HAB-1993-4303
Rioux J.D., Rauch J., Zdarsky E., Newkirk M.M.
Molecular characterization of the GM 4672 human lymphoblastoid cell line and analysis of its use as a fusion partner in the generation of human-human hybridoma autoantibodies.
Hum. Antibodies Hybridomas 4:107-114(1993)

PubMed=8357959; DOI=10.3233/HAB-1993-4301
Denomme G.A., Mahmoudi M., Edwards J.Y., Massicotte H., Cairns E., Bell D.A.
Immunoglobulin V region heavy and light chain gene sequences of the lymphoblastoid cell line GM 4672.
Hum. Antibodies Hybridomas 4:98-103(1993)

Cell line collections (Providers) Coriell; GM04672
Cell line databases/resources CLO; CLO_0019017
Encyclopedic resources Wikidata; Q54847545
Entry history
Entry creation11-Feb-2013
Last entry update05-Oct-2023
Version number19