ID   GM1500-6TG-A11
AC   CVCL_H615
AS   CVCL_F607
SY   GM1500 6TG-A11; GM 1500 6TG-A11; GM 1500 6TG A11; GM1500 6TG A-11; GM 1500 6TG-A1 1; 6TG-A11; GM04672; GM 4672; GM4672; GM04672B
DR   CLO; CLO_0019017
DR   Coriell; GM04672
DR   Wikidata; Q54847545
RX   CelloPub=CLPUB00447;
RX   Patent=US4608337;
RX   PubMed=6350451;
RX   PubMed=6864164;
RX   PubMed=6969366;
RX   PubMed=7085884;
RX   PubMed=7689347;
RX   PubMed=8357959;
CC   Group: Hybridoma fusion partner cell line.
CC   Group: Patented cell line.
CC   Problematic cell line: Misclassified. Parent cell line (GM01500) was originally thought to be a myeloma cell line but is a B-lymphoblastoid cell line.
CC   Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-8032.
CC   Population: Caucasian.
CC   Characteristics: Secretes IgG2 kappa (Coriell=GM04672).
CC   Selected for resistance to: ChEBI; CHEBI:9555; Tioguanine (6-thioguanine; 6-TG).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Transformant: ChEBI; CHEBI:23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
CC   Misspelling: GM1500-GTG-A11; Note=Occasionally.
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_D870 ! GM01500
SX   Male
AG   Age unspecified
CA   Transformed cell line
DT   Created: 11-02-13; Last updated: 05-10-23; Version: 19
//
RX   CelloPub=CLPUB00447;
RA   Mulivor R.A., Suchy S.F.;
RT   "1992/1993 catalog of cell lines. NIGMS human genetic mutant cell
RT   repository. 16th edition. October 1992.";
RL   (In) Institute for Medical Research (Camden, N.J.) NIH 92-2011; pp.1-918; National Institutes of Health; Bethesda (1992).
//
RX   Patent=US4608337;
RA   Croce C.M.;
RT   "Human hybridomas and the production of human monoclonal antibodies by
RT   human hybridomas.";
RL   Patent number US4608337, 26-Aug-1986.
//
RX   PubMed=6350451; DOI=10.4049/jimmunol.131.3.1201;
RA   Abrams P.G., Knost J.A., Clarke G., Wilburn S., Oldham R.K.,
RA   Foon K.A.;
RT   "Determination of the optimal human cell lines for development of
RT   human hybridomas.";
RL   J. Immunol. 131:1201-1204(1983).
//
RX   PubMed=6864164; DOI=10.1084/jem.158.1.53;
RA   Houghton A.N., Brooks H., Cote R.J., Taormina M.C., Oettgen H.F.,
RA   Old L.J.;
RT   "Detection of cell surface and intracellular antigens by human
RT   monoclonal antibodies. Hybrid cell lines derived from lymphocytes of
RT   patients with malignant melanoma.";
RL   J. Exp. Med. 158:53-65(1983).
//
RX   PubMed=6969366; DOI=10.1038/288488a0;
RA   Croce C.M., Linnenbach A., Hall W., Steplewski Z., Koprowski H.;
RT   "Production of human hybridomas secreting antibodies to measles
RT   virus.";
RL   Nature 288:488-489(1980).
//
RX   PubMed=7085884; DOI=10.1172/JCI110595;
RA   Shoenfeld Y., Hsu-Lin S.C., Gabriels J.E., Silberstein L.E.,
RA   Furie B.C., Furie B.E., Stollar B.D., Schwartz R.S.;
RT   "Production of autoantibodies by human-human hybridomas.";
RL   J. Clin. Invest. 70:205-208(1982).
//
RX   PubMed=7689347; DOI=10.3233/HAB-1993-4303;
RA   Rioux J.D., Rauch J., Zdarsky E., Newkirk M.M.;
RT   "Molecular characterization of the GM 4672 human lymphoblastoid cell
RT   line and analysis of its use as a fusion partner in the generation of
RT   human-human hybridoma autoantibodies.";
RL   Hum. Antibodies Hybridomas 4:107-114(1993).
//
RX   PubMed=8357959; DOI=10.3233/HAB-1993-4301;
RA   Denomme G.A., Mahmoudi M., Edwards J.Y., Massicotte H., Cairns E.,
RA   Bell D.A.;
RT   "Immunoglobulin V region heavy and light chain gene sequences of the
RT   lymphoblastoid cell line GM 4672.";
RL   Hum. Antibodies Hybridomas 4:98-103(1993).
//