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Cellosaurus TRAMP-C1A (CVCL_H593)

[Text version]
Cell line name TRAMP-C1A
Synonyms TRAMP.C1A; TRAMP C1A; C1A
Accession CVCL_H593
Resource Identification Initiative To cite this cell line use: TRAMP-C1A (RRID:CVCL_H593)
Comments Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; SV40 large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Prostate; UBERON=UBERON_0002367.
Disease Carcinoma of the mouse prostate gland (NCIt: C21732)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6-TgN(TRAMP)8247Ng.
Hierarchy Parent: CVCL_3614 (TRAMP-C1)
Sex of cell Male
Age at sampling 32W
Category Cancer cell line
Publications

PubMed=11063747; DOI=10.1074/jbc.M008207200
Han G.-Z., Foster B.A., Mistry S., Buchanan G., Harris J.M., Tilley W.D., Greenberg N.M.
Hormone status selects for spontaneous somatic androgen receptor variants that demonstrate specific ligand and cofactor dependent activities in autochthonous prostate cancer.
J. Biol. Chem. 276:11204-11213(2001)

PubMed=14559809
Freeman K.W., Gangula R.D., Welm B.E., Ozen M., Foster B.A., Rosen J.M., Ittmann M., Greenberg N.M., Spencer D.M.
Conditional activation of fibroblast growth factor receptor (FGFR) 1, but not FGFR2, in prostate cancer cells leads to increased osteopontin induction, extracellular signal-regulated kinase activation, and in vivo proliferation.
Cancer Res. 63:6237-6243(2003)

Cross-references
Chemistry resources ChEMBL-Cells; CHEMBL3307772
ChEMBL-Targets; CHEMBL614367
PubChem_Cell_line; CVCL_H593
Encyclopedic resources Wikidata; Q54972947
Entry history
Entry creation11-Feb-2013
Last entry update10-Sep-2024
Version number11