ID   TRAMP-C1A
AC   CVCL_H593
SY   TRAMP.C1A; TRAMP C1A; C1A
DR   ChEMBL-Cells; CHEMBL3307772
DR   ChEMBL-Targets; CHEMBL614367
DR   PubChem_Cell_line; CVCL_H593
DR   Wikidata; Q54972947
RX   PubMed=11063747;
RX   PubMed=14559809;
CC   Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Prostate; UBERON=UBERON_0002367.
CC   Breed/subspecies: C57BL/6-TgN(TRAMP)8247Ng.
DI   NCIt; C21732; Carcinoma of the mouse prostate gland
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_3614 ! TRAMP-C1
SX   Male
AG   32W
CA   Cancer cell line
DT   Created: 11-02-13; Last updated: 10-09-24; Version: 11
//
RX   PubMed=11063747; DOI=10.1074/jbc.M008207200;
RA   Han G.-Z., Foster B.A., Mistry S., Buchanan G., Harris J.M.,
RA   Tilley W.D., Greenberg N.M.;
RT   "Hormone status selects for spontaneous somatic androgen receptor
RT   variants that demonstrate specific ligand and cofactor dependent
RT   activities in autochthonous prostate cancer.";
RL   J. Biol. Chem. 276:11204-11213(2001).
//
RX   PubMed=14559809;
RA   Freeman K.W., Gangula R.D., Welm B.E., Ozen M., Foster B.A.,
RA   Rosen J.M., Ittmann M., Greenberg N.M., Spencer D.M.;
RT   "Conditional activation of fibroblast growth factor receptor (FGFR) 1,
RT   but not FGFR2, in prostate cancer cells leads to increased osteopontin
RT   induction, extracellular signal-regulated kinase activation, and in
RT   vivo proliferation.";
RL   Cancer Res. 63:6237-6243(2003).
//