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Cellosaurus MDA-1386Ln (CVCL_H541)

[Text version]
Cell line name MDA-1386Ln
Synonyms MDA-1386LN; MDA1386LN; MDA1386Ln; 1386LN; 1386Ln
Accession CVCL_H541
Resource Identification Initiative To cite this cell line use: MDA-1386Ln (RRID:CVCL_H541)
Comments Part of: MD Anderson Cell Lines Project.
Omics: Deep exome analysis.
Omics: Protein expression by reverse-phase protein arrays.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Disease Hypopharyngeal squamous cell carcinoma (NCIt: C4043)
Squamous cell carcinoma of the hypopharynx (ORDO: Orphanet_494547)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_6979 ! MDA-1386
CVCL_H542 ! MDA-1386Tu
Sex of cell Male
Age at sampling 72Y
Category Cancer cell line
STR profile Source(s): PubMed=21868764

Markers:
AmelogeninX
CSF1PO11
D5S81812
D7S8208,12
D13S31711
D16S5399,13
TH019
TPOX8
vWA20

Run an STR similarity search on this cell line
Web pages https://tcpaportal.org/mclp/
Publications

PubMed=14724901; DOI=10.1002/hed.10344
Wreesmann V.B., Wang D., Goberdhan A., Prasad M., Ngai I., Schnaser E.A., Sacks P.G., Singh B.
Genetic abnormalities associated with nodal metastasis in head and neck cancer.
Head Neck 26:10-15(2004)

PubMed=15641986; DOI=10.1111/j.1600-0714.2004.00258.x
Vigneswaran N., Wu J., Sacks P.G., Gilcrease M., Zacharias W.
Microarray gene expression profiling of cell lines from primary and metastatic tongue squamous cell carcinoma: possible insights from emerging technology.
J. Oral Pathol. Med. 34:77-86(2005)

PubMed=21868764; DOI=10.1158/1078-0432.CCR-11-0690; PMCID=PMC3229662
Zhao M., Sano D., Pickering C.R., Jasser S.A., Henderson Y.C., Clayman G.L., Sturgis E.M., Ow T.J., Lotan R., Carey T.E., Sacks P.G., Grandis J.R., Sidransky D., Heldin N.-E., Myers J.N.
Assembly and initial characterization of a panel of 85 genomically validated cell lines from diverse head and neck tumor sites.
Clin. Cancer Res. 17:7248-7264(2011)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076
Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P., Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

PubMed=29156801; DOI=10.18632/oncotarget.21174; PMCID=PMC5689691
Kalu N.N., Mazumdar T., Peng S.-H., Shen L., Sambandam V., Rao X.-Y., Xi Y.-X., Li L.-R., Qi Y., Gleber-Netto F.O., Patel A., Wang J., Frederick M.J., Myers J.N., Pickering C.R., Johnson F.M.
Genomic characterization of human papillomavirus-positive and -negative human squamous cell cancer cell lines.
Oncotarget 8:86369-86383(2017)

Cross-references
Encyclopedic resources Wikidata; Q54904551
Polymorphism and mutation databases Cosmic; 2131849
Cosmic; 2439757
Entry history
Entry creation11-Feb-2013
Last entry update10-Sep-2024
Version number19