Cellosaurus cell line MDA-1386 (CVCL

Cross-references
Cell line name	MDA-1386
Synonyms	MDA 1386; MDA1386
Accession	CVCL_6979
Resource Identification Initiative	To cite this cell line use: MDA-1386 (RRID:CVCL_6979)
Sequence variations	Mutation; HGNC; 11998; TP53; Simple; p.Arg280Pro (c.838_839AG>CC); Zygosity=Unspecified (PubMed=7927946). Mutation; HGNC; 11998; TP53; Simple; p.Arg282Trp (c.844C>T); ClinVar=VCV000012364; Zygosity=Unspecified (PubMed=7927946).
Disease	Hypopharyngeal squamous cell carcinoma (NCIt: C4043) Squamous cell carcinoma of the hypopharynx (ORDO: Orphanet_494547)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_H541 ! MDA-1386Ln CVCL_H542 ! MDA-1386Tu
Sex of cell	Male
Age at sampling	72Y
Category	Cancer cell line
Publications	PubMed=7927946; DOI=10.1002/ijc.2910590316 Xu L., Davidson B.J., Murty V.V.V.S., Li R.-G., Sacks P.G., Garin-Chesa P., Schantz S.P., Chaganti R.S.K. TP53 gene mutations and CCND1 gene amplification in head and neck squamous cell carcinoma cell lines. Int. J. Cancer 59:383-387(1994) PubMed=11389082 Singh B., Gogineni S.K., Sacks P.G., Shaha A.R., Shah J.P., Stoffel A., Rao P.H. Molecular cytogenetic characterization of head and neck squamous cell carcinoma and refinement of 3q amplification. Cancer Res. 61:4506-4513(2001)
Cell line databases/resources	cancercelllines; CVCL_6979
Encyclopedic resources	Wikidata; Q54904550
Polymorphism and mutation databases	IARC_TP53; 3547
Entry history
Entry creation	04-Apr-2012
Last entry update	05-Oct-2023
Version number	15