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Cellosaurus MDA-1386 (CVCL_6979)

[Text version]
Cell line name MDA-1386
Synonyms MDA 1386; MDA1386
Accession CVCL_6979
Resource Identification Initiative To cite this cell line use: MDA-1386 (RRID:CVCL_6979)
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg280Pro (c.838_839AG>CC); Zygosity=Unspecified (PubMed=7927946).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg282Trp (c.844C>T); ClinVar=VCV000012364; Zygosity=Unspecified (PubMed=7927946).
Disease Hypopharyngeal squamous cell carcinoma (NCIt: C4043)
Squamous cell carcinoma of the hypopharynx (ORDO: Orphanet_494547)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_H541 ! MDA-1386Ln
CVCL_H542 ! MDA-1386Tu
Sex of cell Male
Age at sampling 72Y
Category Cancer cell line
Publications

PubMed=7927946; DOI=10.1002/ijc.2910590316
Xu L., Davidson B.J., Murty V.V.V.S., Li R.-G., Sacks P.G., Garin-Chesa P., Schantz S.P., Chaganti R.S.K.
TP53 gene mutations and CCND1 gene amplification in head and neck squamous cell carcinoma cell lines.
Int. J. Cancer 59:383-387(1994)

PubMed=11389082
Singh B., Gogineni S.K., Sacks P.G., Shaha A.R., Shah J.P., Stoffel A., Rao P.H.
Molecular cytogenetic characterization of head and neck squamous cell carcinoma and refinement of 3q amplification.
Cancer Res. 61:4506-4513(2001)

Cross-references
Cell line databases/resources cancercelllines; CVCL_6979
Encyclopedic resources Wikidata; Q54904550
Polymorphism and mutation databases IARC_TP53; 3547
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number16