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Cellosaurus FE-8 (CVCL_GS30)

[Text version]
Cell line name FE-8
Synonyms FE8
Accession CVCL_GS30
Resource Identification Initiative To cite this cell line use: FE-8 (RRID:CVCL_GS30)
Comments Selected for resistance to: ChEBI; CHEBI_9555; Tioguanine (6-thioguanine; 6-TG).
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:5173; HRAS (Note=With p.Gly12Val).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Fischer 344; RS=RS:0000215.
Hierarchy Parent: CVCL_4086 (208F)
Sex of cell Sex unspecified
Age at sampling Embryo
Category Transformed cell line
Publications

PubMed=3533793; DOI=10.1002/ijc.2910380513
Griegel S., Traub O., Willecke K., Schaefer R.
Suppression and re-expression of transformed phenotype in hybrids of HA-ras-1-transformed rat-1 cells and early-passage rat embryonic fibroblasts.
Int. J. Cancer 38:697-705(1986)

PubMed=3125552; DOI=10.1073/pnas.85.5.1590; PMCID=PMC279819
Schaefer R., Iyer J., Iten E., Nirkko A.C.
Partial reversion of the transformed phenotype in HRAS-transfected tumorigenic cells by transfer of a human gene.
Proc. Natl. Acad. Sci. U.S.A. 85:1590-1594(1988)

Cross-references
Cell line databases/resources TOKU-E; 3546
Encyclopedic resources Wikidata; Q54834714
Entry history
Entry creation26-Sep-2016
Last entry update19-Dec-2024
Version number12