ID   FE-8
AC   CVCL_GS30
SY   FE8
DR   TOKU-E; 3546
DR   Wikidata; Q54834714
RX   PubMed=3125552;
RX   PubMed=3533793;
CC   Selected for resistance to: ChEBI; CHEBI_9555; Tioguanine (6-thioguanine; 6-TG).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:5173; HRAS (Note=With p.Gly12Val).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
CC   Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922.
CC   Cell type: Fibroblast; CL=CL_0000057.
CC   Breed/subspecies: Fischer 344; RS=RS:0000215.
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
HI   CVCL_4086 ! 208F
SX   Sex unspecified
AG   Embryo
CA   Transformed cell line
DT   Created: 26-09-16; Last updated: 19-12-24; Version: 12
//
RX   PubMed=3125552; DOI=10.1073/pnas.85.5.1590; PMCID=PMC279819;
RA   Schaefer R., Iyer J., Iten E., Nirkko A.C.;
RT   "Partial reversion of the transformed phenotype in HRAS-transfected
RT   tumorigenic cells by transfer of a human gene.";
RL   Proc. Natl. Acad. Sci. U.S.A. 85:1590-1594(1988).
//
RX   PubMed=3533793; DOI=10.1002/ijc.2910380513;
RA   Griegel S., Traub O., Willecke K., Schaefer R.;
RT   "Suppression and re-expression of transformed phenotype in hybrids of
RT   HA-ras-1-transformed rat-1 cells and early-passage rat embryonic
RT   fibroblasts.";
RL   Int. J. Cancer 38:697-705(1986).
//