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Cellosaurus SW732 (CVCL_F651)

[Text version]
Cell line name SW732
Synonyms SW-732; SW 732
Accession CVCL_F651
Resource Identification Initiative To cite this cell line use: SW732 (RRID:CVCL_F651)
Comments Problematic cell line: Contaminated. Shown to be a SW480 (or SW620) derivative (PubMed=288927; PubMed=20143388). Originally thought to originate from a 67 year old female patient with a cervical squamous cell carcinoma metastasized to the lung.
From: Scott and White Clinic; Temple; USA.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00093.
Population: Caucasian.
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations
  • Mutation; HGNC; 583; APC; Simple; p.Gln1338Ter (c.4012C>T); ClinVar=VCV000000801; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Pro309Ser (c.925C>T); ClinVar=VCV000458575; Zygosity=Heterozygous (from parent cell line).
HLA typing Source: PubMed=77569
Class I
HLA-AA*02,09
HLA-BB*07,w22
HLA-CC*w03,w06
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0546 (SW480)
Sex of cell Male
Age at sampling 51Y
Category Cancer cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx
Publications

PubMed=327080; DOI=10.1093/jnci/59.1.221
Fogh J., Fogh J.M., Orfeo T.
One hundred and twenty-seven cultured human tumor cell lines producing tumors in nude mice.
J. Natl. Cancer Inst. 59:221-226(1977)

PubMed=833871; DOI=10.1093/jnci/58.2.209
Fogh J., Wright W.C., Loveless J.D.
Absence of HeLa cell contamination in 169 cell lines derived from human tumors.
J. Natl. Cancer Inst. 58:209-214(1977)

PubMed=77569; DOI=10.1111/j.1399-0039.1978.tb01259.x
Espmark J.A., Ahlqvist-Roth L., Sarne L., Persson A.
Tissue typing of cells in culture. III. HLA antigens of established human cell lines. Attempts at typing by the mixed hemadsorption technique.
Tissue Antigens 11:279-286(1978)

PubMed=288927; DOI=10.1093/jnci/63.3.635
Leibovitz A., Wright W.C., Pathak S., Siciliano M.J., Daniels W.P., Fogh H., Fogh J.
Detection and analysis of a glucose 6-phosphate dehydrogenase phenotype B cell line contamination.
J. Natl. Cancer Inst. 63:635-645(1979)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cross-references
Cell line databases/resources cancercelllines; CVCL_F651
Biological sample resources BioSample; SAMN03151934
Encyclopedic resources Wikidata; Q54971200
Entry history
Entry creation11-Feb-2013
Last entry update05-Oct-2023
Version number26