Cell line name |
SW732 |
Synonyms |
SW-732; SW 732 |
Accession |
CVCL_F651 |
Resource Identification Initiative |
To cite this cell line use: SW732 (RRID:CVCL_F651) |
Comments |
Problematic cell line: Contaminated. Shown to be a SW480 (or SW620) derivative (PubMed=288927; PubMed=20143388). Originally thought to originate from a 67 year old female patient with a cervical squamous cell carcinoma metastasized to the lung. From: Scott and White Clinic; Temple; USA. Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00093. Population: Caucasian. Derived from site: In situ; Colon; UBERON=UBERON_0001155. |
Sequence variations |
- Mutation; HGNC; HGNC:583; APC; Simple; p.Gln1338Ter (c.4012C>T); ClinVar=VCV000000801; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro309Ser (c.925C>T); ClinVar=VCV000458575; Zygosity=Heterozygous (from parent cell line).
|
HLA typing |
Source: PubMed=77569
Class I | HLA-A | A*02,09 | HLA-B | B*07,w22 | HLA-C | C*w03,w06 |
|
Disease |
Colon adenocarcinoma (NCIt: C4349) |
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Hierarchy |
Parent: CVCL_0546 (SW480) |
Sex of cell |
Male |
Age at sampling |
51Y |
Category |
Cancer cell line |
Web pages |
https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx |
Publications | PubMed=327080; DOI=10.1093/jnci/59.1.221 Fogh J., Fogh J.M., Orfeo T. One hundred and twenty-seven cultured human tumor cell lines producing tumors in nude mice. J. Natl. Cancer Inst. 59:221-226(1977) PubMed=833871; DOI=10.1093/jnci/58.2.209 Fogh J., Wright W.C., Loveless J.D. Absence of HeLa cell contamination in 169 cell lines derived from human tumors. J. Natl. Cancer Inst. 58:209-214(1977) PubMed=77569; DOI=10.1111/j.1399-0039.1978.tb01259.x Espmark J.A., Ahlqvist-Roth L., Sarne L., Persson A. Tissue typing of cells in culture. III. HLA antigens of established human cell lines. Attempts at typing by the mixed hemadsorption technique. Tissue Antigens 11:279-286(1978) PubMed=288927; DOI=10.1093/jnci/63.3.635 Leibovitz A., Wright W.C., Pathak S., Siciliano M.J., Daniels W.P., Fogh H., Fogh J. Detection and analysis of a glucose 6-phosphate dehydrogenase phenotype B cell line contamination. J. Natl. Cancer Inst. 63:635-645(1979) PubMed=20143388; DOI=10.1002/ijc.25242 Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I. Check your cultures! A list of cross-contaminated or misidentified cell lines. Int. J. Cancer 127:1-8(2010) |
Cross-references |
Cell line databases/resources |
cancercelllines; CVCL_F651
|
Biological sample resources |
BioSample; SAMN03151934
|
Encyclopedic resources |
Wikidata; Q54971200
|
Entry history |
Entry creation | 11-Feb-2013 |
Last entry update | 19-Dec-2024 |
Version number | 28 |
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