Cellosaurus cell line Caco-2(Cas9) (CVCL

Entry history
Cell line name	Caco-2(Cas9)
Accession	CVCL_E7J1
Resource Identification Initiative	To cite this cell line use: Caco-2(Cas9) (RRID:CVCL_E7J1)
Comments	Population: Caucasian. Genetic integration: Method=Transduction; Gene=UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9. Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations	Mutation; HGNC; HGNC:583; APC; Simple; p.Gln1367Ter (c.4099C>T); ClinVar=VCV000376060; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Gly245Ala (c.734G>C); Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:6770; SMAD4; Simple; p.Asp351His (c.1051G>C); ClinVar=VCV000375998; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu204Ter (c.610G>T); ClinVar=VCV000977783; Zygosity=Homozygous (from parent cell line).
Disease	Colon adenocarcinoma (NCIt: C4349)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0025 (Caco-2)
Sex of cell	Male
Age at sampling	72Y
Category	Cancer cell line
Web pages	Provider; BRICS; ECC3016; http://www.brics.ac.cn/cell/template/cell/cell_detail.html?id=3950
Entry creation	10-Apr-2025
Last entry update	10-Apr-2025
Version number	1