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Cellosaurus N2a APP695-N467K (CVCL_E7F3)

[Text version]
Cell line name N2a APP695-N467K
Accession CVCL_E7F3
Resource Identification Initiative To cite this cell line use: N2a APP695-N467K (RRID:CVCL_E7F3)
Comments Genetic integration: Method=Transfection; Gene=HGNC; HGNC:620; APP (Note=Isoform APP695 with p.Asn467Lys).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Derived from site: In situ; Peripheral nervous system; UBERON=UBERON_0000010.
Cell type: Neural crest derived neuroblast; CL=CL_0002676.
Disease Mouse neuroblastoma (NCIt: C21993)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: A/J.
Hierarchy Parent: CVCL_0470 (Neuro-2a)
Sex of cell Male
Category Cancer cell line
Publications

PubMed=30796750; DOI=10.1007/s11064-019-02747-y; PMCID=PMC6525264
Tsatsanis A., Dickens S., Kwok J.C.F., Wong B.X.-W., Duce J.A.
Post translational modulation of beta-amyloid precursor protein trafficking to the cell surface alters neuronal iron homeostasis.
Neurochem. Res. 44:1367-1374(2019)

Cross-references
Cell line collections (Providers) ABM; T6512
Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1