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Cellosaurus VDS-0 (CVCL_E7E3)

[Text version]
Cell line name VDS-0
Synonyms VDS-O; VDSO; VDSO/parental; VDSO/P
Accession CVCL_E7E3
Resource Identification Initiative To cite this cell line use: VDS-0 (RRID:CVCL_E7E3)
Comments Characteristics: Seems to be composed of immature B cells. Does not secretes Ig nor contains intracellular Ig (PubMed=3018084).
Doubling time: 28 hours (PubMed=9563901).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: B-cell; CL=CL_0000236.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_E7E8 (VDS)
Children:
CVCL_E7E4 (VDSO/CMV-8)CVCL_E7E9 (VDSO/CMV-9)CVCL_E7E5 (VDSO/E6-18)
CVCL_E7EA (VDSO/E6-19)
Category Transformed cell line
Publications

PubMed=3018084; DOI=10.4049/jimmunol.137.6.2037
Tosato G., Marti G.E., Yarchoan R., Heilman C.A., Wang F., Pike S.E., Korsmeyer S.J., Siminovitch K.A.
Epstein-Barr virus immortalization of normal cells of B cell lineage with nonproductive, rearranged immunoglobulin genes.
J. Immunol. 137:2037-2042(1986)

PubMed=9563901
Fan S.-J., Cherney B.W., Reinhold W.C., Rucker K., O'Connor P.M.
Disruption of p53 function in immortalized human cells does not affect survival or apoptosis after taxol or vincristine treatment.
Clin. Cancer Res. 4:1047-1054(1998)

PubMed=9973220
Gutierrez M.I., Cherney B.W., Hussain A., Mostowski H.S., Tosato G., Magrath I.T., Bhatia K.G.
Bax is frequently compromised in Burkitt's lymphomas with irreversible resistance to Fas-induced apoptosis.
Cancer Res. 59:696-703(1999)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1