Cellosaurus logo
expasy logo

Cellosaurus UM-SCC-12-Luc-YFP (CVCL_E6YS)

[Text version]
Cell line name UM-SCC-12-Luc-YFP
Synonyms UMSCC12Luc
Accession CVCL_E6YS
Resource Identification Initiative To cite this cell line use: UM-SCC-12-Luc-YFP (RRID:CVCL_E6YS)
Comments Characteristics: Transfected with a luciferase-YFP fusion protein whose expression is under the control of a CMV promoter (PubMed=22265717).
Genetic integration: Method=Transfection; Gene=UniProtKB; P08659; Firefly luciferase.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Genetic integration: Method=Transfection/transduction; Gene=FPbase; 8DNLG; YFP (Note=EYFP, yellow fluorescent protein derived from GFP).
Derived from site: In situ; Larynx; UBERON=UBERON_0001737.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gln104Ter (c.310C>T); ClinVar=VCV000566924; Zygosity=Unspecified (from parent cell line).
Disease Laryngeal squamous cell carcinoma (NCIt: C4044)
Squamous cell carcinoma of the larynx (ORDO: Orphanet_494550)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_7717 (UM-SCC-12)
Sex of cell Male
Age at sampling 71Y
Category Cancer cell line
Publications

PubMed=22265717; DOI=10.1016/j.oraloncology.2011.12.012; PMCID=PMC3350825
Martin C.K., Dirksen W.P., Shu S.T., Werbeck J.L., Thudi N.K., Yamaguchi M., Wolfe T.D., Heller K.N., Rosol T.J.
Characterization of bone resorption in novel in vitro and in vivo models of oral squamous cell carcinoma.
Oral Oncol. 48:491-499(2012)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1