ID   UM-SCC-12-Luc-YFP
AC   CVCL_E6YS
SY   UMSCC12Luc
RX   PubMed=22265717;
CC   Characteristics: Transfected with a luciferase-YFP fusion protein whose expression is under the control of a CMV promoter (PubMed=22265717).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gln104Ter (c.310C>T); ClinVar=VCV000566924; Zygosity=Unspecified (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=FPbase; 8DNLG; YFP (Note=EYFP, yellow fluorescent protein derived from GFP).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
CC   Derived from site: In situ; Larynx; UBERON=UBERON_0001737.
DI   NCIt; C4044; Laryngeal squamous cell carcinoma
DI   ORDO; Orphanet_494550; Squamous cell carcinoma of the larynx
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_7717 ! UM-SCC-12
SX   Male
AG   71Y
CA   Cancer cell line
DT   Created: 10-04-25; Last updated: 14-08-25; Version: 2
//
RX   PubMed=22265717; DOI=10.1016/j.oraloncology.2011.12.012; PMCID=PMC3350825;
RA   Martin, Chelsea K.
RA   Dirksen, Wessel P.
RA   Shu, Sherry T.
RA   Werbeck, Jillian L.
RA   Thudi, Nanda K.
RA   Yamaguchi, Mamoru
RA   Wolfe, Tobie Dianne
RA   Heller, Kristin N.
RA   Rosol, Thomas John
RT   "Characterization of bone resorption in novel in vitro and in vivo
RT   models of oral squamous cell carcinoma.";
RL   Oral Oncol. 48:491-499(2012).
//