Cellosaurus CRBL (CVCL_E6DZ)
| Cell line name | CRBL |
|---|---|
| Accession | CVCL_E6DZ |
| Resource Identification Initiative | To cite this cell line use: CRBL (RRID:CVCL_E6DZ) |
| Comments | Characteristics: Expresses both neuronal and glial cell markers as well as a considerable level of cellular prion protein (PRNP). Susceptible to infections by strain SMB prions (PubMed=18395703). Doubling time: 15.6 +- 2.5 hours (Note=At 10th passage in 10% FBS), 11.6 hours (Note=At 60th passage in 10% FBS), 10.6 +- 0.7 hours (Note=At 80th passage in 10% FBS), 23.5 hours (Note=At 10th passage in 2.5% FBS) (PubMed=18395703). Knockout cell: Method=KO mouse; MGI; MGI:98834; Trp53. Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P00552; Transposon Tn5 neo. Derived from site: In situ; Brain, cerebellum; UBERON=UBERON_0002037. |
| Species of origin | Mus musculus (Mouse) (NCBI Taxonomy: 10090) |
| Sex of cell | Sex unspecified |
| Age at sampling | 3M |
| Category | Spontaneously immortalized cell line |
| Publications | PubMed=18395703; DOI=10.1016/j.brainres.2008.02.103; PMCID=PMC2464299 |
| Cross-references | |
| Cell line collections (Providers) | ABM; T0759 |
| Entry history | |
| Entry creation | 10-Apr-2025 |
| Last entry update | 10-Apr-2025 |
| Version number | 1 |