Cellosaurus U2OS-CRISPR-TPR-SNAPf no.2-F01 (CVCL_E6B3)
Cell line name | U2OS-CRISPR-TPR-SNAPf no.2-F01 |
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Synonyms | U2OS-CRISPR-TPR-SNAPf #2-F01; U2OS CRISPR TPR-SNAPf #2-F01 |
Accession | CVCL_E6B3 |
Resource Identification Initiative | To cite this cell line use: U2OS-CRISPR-TPR-SNAPf no.2-F01 (RRID:CVCL_E6B3) |
Comments | Population: Caucasian. Characteristics: Using CRISPR/Cas9D10A TPR has been endogenously tagged in both alleles at the C-terminus with a SNAP-f tag (PubMed=34191541). Genetic integration: Method=CRISPR/Cas9; Gene=HGNC; HGNC:7059; MGMT (Note=With p.Gly183_Asn207del and 20 mutations = SNAP-f-tag). Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979. |
Sequence variations |
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Disease | Osteosarcoma (NCIt: C9145) Osteosarcoma (ORDO: Orphanet_668) |
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
Hierarchy | Parent: CVCL_0042 (U2OS) |
Sex of cell | Female |
Age at sampling | 15Y |
Category | Cancer cell line |
Publications | PubMed=34191541; DOI=10.1091/mbc.E20-11-0728; PMCID=PMC8351745 |
Cross-references | |
Cell line collections (Providers) | CLS; 300667 |
Entry history | |
Entry creation | 10-Apr-2025 |
Last entry update | 10-Apr-2025 |
Version number | 1 |