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Cellosaurus SW480 EGFP clone 2 (CVCL_E5FY)

[Text version]
Cell line name SW480 EGFP clone 2
Synonyms SW480 GFP-alone 2; SW480/cntl 2
Accession CVCL_E5FY
Resource Identification Initiative To cite this cell line use: SW480 EGFP clone 2 (RRID:CVCL_E5FY)
Comments Population: Caucasian.
Genetic integration: Method=Transfection; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations
  • Mutation; HGNC; HGNC:583; APC; Simple; p.Gln1338Ter (c.4012C>T); ClinVar=VCV000000801; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro309Ser (c.925C>T); ClinVar=VCV000458575; Zygosity=Heterozygous (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0546 (SW480)
Sex of cell Male
Age at sampling 51Y
Category Cancer cell line
Publications

PubMed=18714339; DOI=10.1371/journal.pone.0002988; PMCID=PMC2496895
Willis N.D., Cox T.R., Rahman-Casans S.F., Smits K.M., Przyborski S.A., van den Brandt P.A., van Engeland M., Weijenberg M.P., Wilson R.G., de Bruine A.P., Hutchison C.J.
Lamin A/C is a risk biomarker in colorectal cancer.
PLoS ONE 3:e2988.1-e2988.9(2008)

Cross-references
Cell line collections (Providers) CancerTools; 162204
Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1