Cellosaurus cell line ICC11 (CVCL

Cellosaurus ICC11 (CVCL_E4KQ)

Entry history
Cell line name	ICC11
Accession	CVCL_E4KQ
Resource Identification Initiative	To cite this cell line use: ICC11 (RRID:CVCL_E4KQ)
Comments	Part of: Biliary tract cancer cell line atlas. Population: African American.
Sequence variations	Gene fusion; HGNC; HGNC:3689; FGFR2 + HGNC; HGNC:8923; PHGDH; Name(s)=FGFR2-PHGDH (PubMed=39026794). Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Gln219Ter (c.655C>T); Zygosity=Unspecified (PubMed=39026794). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Leu35Cysfs*9 (c.102delC); ClinVar=VCV001072141; Zygosity=Unspecified (PubMed=39026794).
Disease	Intrahepatic cholangiocarcinoma (NCIt: C35417) Cholangiocarcinoma (ORDO: Orphanet_70567)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_A1VB ! ICC10 CVCL_A1UZ ! ICC10-6 CVCL_A1VA ! ICC10-8
Sex of cell	Male
Category	Cancer cell line
Publications	PubMed=39026794; DOI=10.1101/2024.07.04.601970; PMCID=PMC11257448 Vijay V., Karisani N., Shi L., Hung Y.-H., Vu P., Kattel P., Kenney L., Merritt J., Adil R., Wu Q.-B., Zhen Y.-L., Morris R., Kreuzer J., Kathiresan M., Herrera Lopez X.I., Ellis H., Gritti I.G., Lecorgne L., Farag I., Popa A., Shen W., Kato H., Xu Q., Balasooriya E.R., Wu M.-J., Chaturantabut S., Kelley R.K., Cleary J.M., Lawrence M.S., Root D.E., Benes C.H., Deshpande V., Juric D., Sellers W.R., Ferrone C.R., Haas W., Vazquez F., Getz G., Bardeesy N.M. Generation of a biliary tract cancer cell line atlas reveals molecular subtypes and therapeutic targets. bioRxiv 2024:07.04.601970-07.04.601970(2024)
Entry creation	19-Dec-2024
Last entry update	19-Dec-2024
Version number	1