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Cellosaurus ICC10-8 (CVCL_A1VA)

[Text version]
Cell line name ICC10-8
Synonyms ICC108
Accession CVCL_A1VA
Resource Identification Initiative To cite this cell line use: ICC10-8 (RRID:CVCL_A1VA)
Comments Part of: Biliary tract cancer cell line atlas.
Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: African American.
Sequence variations
  • Gene fusion; HGNC; HGNC:3689; FGFR2 + HGNC; HGNC:8923; PHGDH; Name(s)=FGFR2-PHGDH (DepMap=ACH-001836; PubMed=39026794).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Gln219Ter (c.655C>T); Zygosity=Unspecified (DepMap=ACH-001836; PubMed=39026794).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Leu35Cysfs*9 (c.102delC); ClinVar=VCV001072141; Zygosity=Unspecified (DepMap=ACH-001836; PubMed=39026794).
Disease Intrahepatic cholangiocarcinoma (NCIt: C35417)
Cholangiocarcinoma (ORDO: Orphanet_70567)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_A1VB ! ICC10
CVCL_A1UZ ! ICC10-6
CVCL_E4KQ ! ICC11
Sex of cell Male
Category Cancer cell line
STR profile Source(s): DepMap=ACH-001836

Markers:
AmelogeninX
CSF1PO7,10
D3S135817
D5S81812
D7S8208,13
D8S117914,16
D13S3178
D16S53911,13
D18S5112,17
D21S1131,31.2
FGA22
Penta D8,9
Penta E8,12
TH016,7
TPOX8,11
vWA16,18

Run an STR similarity search on this cell line
Publications

PubMed=39026794; DOI=10.1101/2024.07.04.601970; PMCID=PMC11257448
Vijay V., Karisani N., Shi L., Hung Y.-H., Vu P., Kattel P., Kenney L., Merritt J., Adil R., Wu Q.-B., Zhen Y.-L., Morris R., Kreuzer J., Kathiresan M., Herrera Lopez X.I., Ellis H., Gritti I.G., Lecorgne L., Farag I., Popa A., Shen W., Kato H., Xu Q., Balasooriya E.R., Wu M.-J., Chaturantabut S., Kelley R.K., Cleary J.M., Lawrence M.S., Root D.E., Benes C.H., Deshpande V., Juric D., Sellers W.R., Ferrone C.R., Haas W., Vazquez F., Getz G., Bardeesy N.M.
Generation of a biliary tract cancer cell line atlas reveals molecular subtypes and therapeutic targets.
bioRxiv 2024:07.04.601970-07.04.601970(2024)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A1VA
Cell_Model_Passport; SIDM01976
DepMap; ACH-001836
Encyclopedic resources Wikidata; Q105509588
Entry history
Entry creation12-Jan-2021
Last entry update19-Dec-2024
Version number8