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Cellosaurus PA-DUKX.378 (CVCL_E4ID)

[Text version]
Cell line name PA-DUKX.378
Synonyms PA DUKX 378
Accession CVCL_E4ID
Resource Identification Initiative To cite this cell line use: PA-DUKX.378 (RRID:CVCL_E4ID)
Comments Group: Serum/protein free medium cell line.
Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Transformant: NCIt; C44386; Gamma radiation.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Sequence variations
  • Gene deletion; UniProtKB; Q2MH30; Dhfr; Zygosity=Heterozygous (from parent cell line).
  • Mutation; UniProtKB; Q2MH30; Dhfr; Simple; p.Thr137Arg (c.410G>C); Zygosity=Heterozygous (from parent cell line).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_1977 (CHO-DXB11)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=18629924; DOI=10.1002/(SICI)1097-0290(19961120)52:4<518::AID-BIT7>3.0.CO;2-S
Sinacore M.S., Charlebois T.S., Harrison S., Brennan S., Richards T., Hamilton M.A., Scott S., Brodeur S., Oakes P., Leonard M.W., Switzer M., Anagnostopoulos A.K., Foster W.B., Harris A., Jankowski M.A., Bond M.D., Martin S.A., Adamson S.R.
CHO DUKX cell lineages preadapted to growth in serum-free suspension culture enable rapid development of cell culture processes for the manufacture of recombinant proteins.
Biotechnol. Bioeng. 52:518-528(1996)

Entry history
Entry creation19-Dec-2024
Last entry update19-Dec-2024
Version number1