ID   PA-DUKX.378
AC   CVCL_E4ID
SY   PA DUKX 378
RX   PubMed=18629924;
CC   Group: Serum/protein free medium cell line.
CC   Sequence variation: Gene deletion; UniProtKB; Q2MH30; Dhfr; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; UniProtKB; Q2MH30; Dhfr; Simple; p.Thr137Arg (c.410G>C); Zygosity=Heterozygous (from parent cell line).
CC   Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
CC   Transformant: NCIt; C44386; Gamma radiation.
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_1977 ! CHO-DXB11
SX   Female
AG   Adult
CA   Transformed cell line
DT   Created: 19-12-24; Last updated: 19-12-24; Version: 1
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RX   PubMed=18629924; DOI=10.1002/(SICI)1097-0290(19961120)52:4<518::AID-BIT7>3.0.CO;2-S;
RA   Sinacore M.S., Charlebois T.S., Harrison S., Brennan S., Richards T.,
RA   Hamilton M.A., Scott S., Brodeur S., Oakes P., Leonard M.W., Switzer M.,
RA   Anagnostopoulos A.K., Foster W.B., Harris A., Jankowski M.A., Bond M.D.,
RA   Martin S.A., Adamson S.R.;
RT   "CHO DUKX cell lineages preadapted to growth in serum-free suspension
RT   culture enable rapid development of cell culture processes for the
RT   manufacture of recombinant proteins.";
RL   Biotechnol. Bioeng. 52:518-528(1996).
//