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Cellosaurus UAB-iPSC-PKD2-cKO P/null #1 (CVCL_E3XY)

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Cell line name UAB-iPSC-PKD2-cKO P/null #1
Synonyms UABiPGP1-PKD2 conditional knockout permissive orientation over null (P/null)
Accession CVCL_E3XY
Resource Identification Initiative To cite this cell line use: UAB-iPSC-PKD2-cKO P/null #1 (RRID:CVCL_E3XY)
Comments From: University of Alabama at Birmingham - Polycystic Kidney Disease center (UAB-PKD); Birmingham; USA.
Population: Caucasian.
Characteristics: This is a PKD2 conditional knockout permissive orientation over null (P/null) cell line, equivalent to heterozygous null, which can be converted to a homozygous null with Cre or Flp recombinase (UAB-PKD).
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:9009; PKD2 (Note=Heterozygous null that can be converted to homozygous null with Cre or Flp recombinase).
Genetic integration: Method=CRISPR/Cas9; Gene=FPbase; ZERB6; mCherry (Note=Red fluorescent protein derived from drFP583 (dsRed)).
Derived from site: In situ; Arm, skin; UBERON=UBERON_0002427.
Cell type: Fibroblast of skin; CL=CL_0002620.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_F182 (GM23338)
Sex of cell Male
Age at sampling 55Y
Category Induced pluripotent stem cell
Web pages https://www.pkd-rrc.org/downloads/new-uab-ipsc-pkd2-cko-p-null-1/
Entry history
Entry creation19-Dec-2024
Last entry update19-Dec-2024
Version number1