Cellosaurus UAB-iPSC-PKD2-cKO NP/null #1 (CVCL_E3XX)
| Cell line name | UAB-iPSC-PKD2-cKO NP/null #1 |
|---|---|
| Synonyms | UABiPGP1-PKD2 conditional knockout non-permissive orientation over null (NP/null) |
| Accession | CVCL_E3XX |
| Resource Identification Initiative | To cite this cell line use: UAB-iPSC-PKD2-cKO NP/null #1 (RRID:CVCL_E3XX) |
| Comments | From: University of Alabama at Birmingham - Polycystic Kidney Disease center (UAB-PKD); Birmingham; USA. Population: Caucasian. Characteristics: This is a PKD2 conditional knockout non-permissive orientation over null (NP/null) cell line, equivalent to homozygous null, which can be converted to a heterozygous null with Cre (UAB-PKD). Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:9009; PKD2 (Note=Homozygous null that can be converted to heterozygous null with Cre or Flp recombinase). Genetic integration: Method=CRISPR/Cas9; Gene=FPbase; ZERB6; mCherry (Note=Red fluorescent protein derived from drFP583 (dsRed)). Derived from site: In situ; Arm, skin; UBERON=UBERON_0002427. Cell type: Fibroblast of skin; CL=CL_0002620. |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_F182 (GM23338) |
| Sex of cell | Male |
| Age at sampling | 55Y |
| Category | Induced pluripotent stem cell |
| Web pages | https://www.pkd-rrc.org/downloads/new-uab-ipsc-pkd2-cko-np-null-1-3/ |
| Entry history | |
| Entry creation | 19-Dec-2024 |
| Last entry update | 19-Dec-2024 |
| Version number | 1 |