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Cellosaurus Caki-2 DNMT3A KO (CVCL_E3VW)

[Text version]
Cell line name Caki-2 DNMT3A KO
Accession CVCL_E3VW
Resource Identification Initiative To cite this cell line use: Caki-2 DNMT3A KO (RRID:CVCL_E3VW)
Comments Problematic cell line: Misclassified. Parent cell line originally thought to be a clear cell renal cell carcinoma but shown to be from a papillary renal cell carcinoma (PubMed=17409424; PubMed=27993170).
Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:2978; DNMT3A.
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Disease Papillary renal cell carcinoma (NCIt: C6975)
Papillary renal cell carcinoma (ORDO: Orphanet_319298)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0235 (Caki-2)
Sex of cell Male
Age at sampling 69Y
Category Cancer cell line
Publications

PubMed=30897760; DOI=10.3390/cancers11030391; PMCID=PMC6468518
Ramos de Matos M., Posa I., Carvalho F.S., Morais V.A., Grosso A.R., de Almeida S.F.
A systematic pan-cancer analysis of genetic heterogeneity reveals associations with epigenetic modifiers.
Cancers (Basel) 11:391.1-391.17(2019)

Cross-references
Cell line collections (Providers) CancerTools; 160723
Entry history
Entry creation19-Dec-2024
Last entry update19-Dec-2024
Version number1